Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C9H8INO3 |
| Molecular Weight | 305.0692 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)CNC(=O)C1=CC=CC=C1I
InChI
InChIKey=CORFWQGVBFFZHF-UHFFFAOYSA-N
InChI=1S/C9H8INO3/c10-7-4-2-1-3-6(7)9(14)11-5-8(12)13/h1-4H,5H2,(H,11,14)(H,12,13)
Ortho-iodohippurate (also known IODOHIPPURATE) as is used for the determination of effective renal plasma flow. It is a halogen derivative of a compound normally found in human urine, and as the end product of a process of detoxification is synthesized in the body. This compound is nontoxic, when administrated intravenous. In patients with normally functioning kidneys, 85% of the ortho-iodohippurate may be found in the urine 30 minutes after intravenous injection. It is eliminated mainly by tubular secretion.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Simplified methods for estimation of 99mTc-pentetate and 131I-orthoiodohippurate plasma clearance in dogs and cats. | 2001 May-Jun |
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| Validation of neutron activation as a novel method to determine glomerular filtration rate. | 2007 |
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| Glomerular filtration rate measured by (51)Cr-EDTA clearance: Evaluation of captopril-induced changes in hypertensive patients with and without renal artery stenosis. | 2010 Jun |
Patents
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1344305
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ortho-Iodohippuric acid
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3Y68K91A3M
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205-693-5
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SUB14249MIG
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100000077379
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DTXSID8046161
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8614
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DB15445
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D007465
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ACTIVE MOIETY
SALT/SOLVATE (PARENT)
