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Details

Stereochemistry ACHIRAL
Molecular Formula C20H25NO.C2H2O4
Molecular Weight 385.4535
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NORMETHADONE OXALATE

SMILES

OC(=O)C(O)=O.CCC(=O)C(CCN(C)C)(C1=CC=CC=C1)C2=CC=CC=C2

InChI

InChIKey=INMNKGOTEWCRST-UHFFFAOYSA-N
InChI=1S/C20H25NO.C2H2O4/c1-4-19(22)20(15-16-21(2)3,17-11-7-5-8-12-17)18-13-9-6-10-14-18;3-1(4)2(5)6/h5-14H,4,15-16H2,1-3H3;(H,3,4)(H,5,6)

HIDE SMILES / InChI

Description

Normethadone is a derivate of opioid analgetic methadone, used as component of antitussive drops in Canada. Illicit drug.

CNS Activity

CNS Active
3913

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Mu-type opioid receptor
61
Target ID: P33535|||Q64064
Gene ID: 25601.0
Gene Symbol: Oprm1
Target Organism: Rattus norvegicus (Rat)
Agonist
2678
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Approved
8429
Cophylac

Approved Use

Cough
PubMed

PubMed

TitleDatePubMed

Sample Use Guides

In Vivo Use Guide
Cophylac (normethadone HCl 10 mg and p-hydroxyephedrine HCl 20 mg): 15 drops twice daily
Route of Administration: Oral
In Vitro Use Guide
Unknown
Name Type Language
NORMETHADONE OXALATE
Common Name English
3-HEXANONE, 6-(DIMETHYLAMINO)-4,4-DIPHENYL-, ETHANEDIOATE (1:1)
Systematic Name English
3-HEXANONE, 6-(DIMETHYLAMINO)-4,4-DIPHENYL-, OXALATE (1:1)
Systematic Name English
6-DIMETHYLAMINO-4,4-DIPHENYL-3-HEXANONE OXALATE
Systematic Name English
Code System Code Type Description
PUBCHEM
119025858
Created by admin on Sat Dec 16 10:28:50 GMT 2023 , Edited by admin on Sat Dec 16 10:28:50 GMT 2023
PRIMARY
CAS
6202-36-4
Created by admin on Sat Dec 16 10:28:50 GMT 2023 , Edited by admin on Sat Dec 16 10:28:50 GMT 2023
PRIMARY
FDA UNII
3R57N9908J
Created by admin on Sat Dec 16 10:28:50 GMT 2023 , Edited by admin on Sat Dec 16 10:28:50 GMT 2023
PRIMARY
PARENT (SALT/SOLVATE)
Structure of NORMETHADONE
SUBSTANCE RECORD
Structure of NORMETHADONE OXALATE
NIH
NCATS
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