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Details

Stereochemistry ACHIRAL
Molecular Formula C20H25NO.C2H2O4
Molecular Weight 385.4535
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NORMETHADONE OXALATE

SMILES

OC(=O)C(O)=O.CCC(=O)C(CCN(C)C)(C1=CC=CC=C1)C2=CC=CC=C2

InChI

InChIKey=INMNKGOTEWCRST-UHFFFAOYSA-N
InChI=1S/C20H25NO.C2H2O4/c1-4-19(22)20(15-16-21(2)3,17-11-7-5-8-12-17)18-13-9-6-10-14-18;3-1(4)2(5)6/h5-14H,4,15-16H2,1-3H3;(H,3,4)(H,5,6)

HIDE SMILES / InChI
Molecular Formula C2H2O4
Molecular Weight 90.0349
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C20H25NO
Molecular Weight 295.4186
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Normethadone is a derivate of opioid analgetic methadone, used as component of antitussive drops in Canada. Illicit drug.

CNS Activity

CNS Active
3913

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Mu-type opioid receptor
61
Target ID: P33535|||Q64064
Gene ID: 25601.0
Gene Symbol: Oprm1
Target Organism: Rattus norvegicus (Rat)
Agonist
2678
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Approved
8429
Cophylac

Approved Use

Cough
PubMed

PubMed

TitleDatePubMed

Sample Use Guides

In Vivo Use Guide
Cophylac (normethadone HCl 10 mg and p-hydroxyephedrine HCl 20 mg): 15 drops twice daily
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 10:28:50 GMT 2023
Edited
by admin
on Sat Dec 16 10:28:50 GMT 2023
Record UNII
3R57N9908J
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NORMETHADONE OXALATE
Common Name English
3-HEXANONE, 6-(DIMETHYLAMINO)-4,4-DIPHENYL-, ETHANEDIOATE (1:1)
Systematic Name English
3-HEXANONE, 6-(DIMETHYLAMINO)-4,4-DIPHENYL-, OXALATE (1:1)
Systematic Name English
6-DIMETHYLAMINO-4,4-DIPHENYL-3-HEXANONE OXALATE
Systematic Name English
Code System Code Type Description
PUBCHEM
119025858
Created by admin on Sat Dec 16 10:28:50 GMT 2023 , Edited by admin on Sat Dec 16 10:28:50 GMT 2023
PRIMARY
CAS
6202-36-4
Created by admin on Sat Dec 16 10:28:50 GMT 2023 , Edited by admin on Sat Dec 16 10:28:50 GMT 2023
PRIMARY
FDA UNII
3R57N9908J
Created by admin on Sat Dec 16 10:28:50 GMT 2023 , Edited by admin on Sat Dec 16 10:28:50 GMT 2023
PRIMARY
Related Record Type Details
Structure of NORMETHADONE
SALT/SOLVATE -> PARENT
Structure of NORMETHADONE
PARENT -> SALT/SOLVATE
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