BEREFRINE

Details

Stereochemistry	EPIMERIC
Molecular Formula	C14H21NO2
Molecular Weight	235.322
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1C[C@H](OC1C(C)(C)C)C2=CC(O)=CC=C2

InChI

InChIKey=ORIOFGXXYYXLNY-UEWDXFNNSA-N

InChI=1S/C14H21NO2/c1-14(2,3)13-15(4)9-12(17-13)10-6-5-7-11(16)8-10/h5-8,12-13,16H,9H2,1-4H3/t12-,13?/m0/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/?2008281 | https://www.ncbi.nlm.nih.gov/pubmed/8272415

Berefrine (also known as phenylephrine oxazolidine), a prodrug of phenylephrine, is a mydriatic agent. Berefrine was developed for improving ocular absorption and reducing systemic side effects.

Approval Year

PubMed

Title	Date	PubMed

Name

Type

Language

BEREFRINE

Official Name

English

PHENOL, 3-(2-(1,1-DIMETHYLETHYL)-3-METHYL-5-OXAZOLIDINYL)-

Systematic Name

English

berefrine [INN]

Common Name

English

M-((2R,5R)-2-TERT-BUTYL-3-METHYL-5-OXAZOLIDINYL)PHENOL MIXTURE WITH M-((2S,5R)-2-TERT-BUTYL-3-METHYL-5-OXAZOLIDINYL)PHENOL

Common Name

English

BEREFRINE [USAN]

Common Name

English

3-((5R)-2-TERT-BUTYL-3-METHYL-1,3-OXAZOLIDIN-5-YL)PHENOL

Systematic Name

English

2-T-BUTYL-3-METHYL-5-(M-HYDROXYPHENYL)-1,3-OXAZOLIDINE

Systematic Name

English

BUREFRINE

Common Name

English

Code System Code Type Description

WIKIPEDIA

Berefrine