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Details

Stereochemistry ACHIRAL
Molecular Formula C20H35NO2.ClH
Molecular Weight 357.958
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIHEXYVERINE HYDROCHLORIDE

SMILES

Cl.O=C(OCCN1CCCCC1)C2(CCCCC2)C3CCCCC3

InChI

InChIKey=AQFATCCHOXBYNK-UHFFFAOYSA-N
InChI=1S/C20H35NO2.ClH/c22-19(23-17-16-21-14-8-3-9-15-21)20(12-6-2-7-13-20)18-10-4-1-5-11-18;/h18H,1-17H2;1H

HIDE SMILES / InChI

Description

Dihexyverine (Metaspas, Spasmodex) is an anticholinergic and direct smooth muscle relaxant (spasmolytic). Dihexyverine is sold in France under the brand name Spasmodex. It is indicated for the treatment of the gastrointestinal tract disorders. Dihexyverine is a muscarinic acetylcholine receptor antagonist.

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
[Trial therapy of spastic cough with a new synthetic antispasmodic: dihexyverine].
1955 Dec 25
[Preliminary clinical study on the use of dihexyverine in obstetrics].
1962 Nov 24
Patents

Patents

20050281772
7

Sample Use Guides

In Vivo Use Guide
One hundred and five patients constituted the series: 31 were primiparae, 27 secundiparae and 47 multiparae. The majority of these (95) received one intramuscular injection (10 mg) of dihexyverine.
Route of Administration: Intramuscular
Name Type Language
DIHEXYVERINE HYDROCHLORIDE
MART.   MI   USAN   WHO-DD  
USAN  
Official Name English
2-Piperidinoethyl ester of bicyclohexyl-1-carboxylic acid hydrochloride
Common Name English
DIHEXYVERINE HYDROCHLORIDE [MART.]
Common Name English
DIHEXYVERINE HYDROCHLORIDE [MI]
Common Name English
(1,1'-BICYCLOHEXYL)-1-CARBOXYLIC ACID, 2-(1-PIPERIDINYL)ETHYL ESTER HYDROCHLORIDE
Common Name English
JL-1078
Code English
DIHEXYVERINE HYDROCHLORIDE [USAN]
Common Name English
Dihexyverine hydrochloride [WHO-DD]
Common Name English
DIHEXYVERINE HCL
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29704
Created by admin on Fri Dec 15 15:36:13 GMT 2023 , Edited by admin on Fri Dec 15 15:36:13 GMT 2023
NCI_THESAURUS C29698
Created by admin on Fri Dec 15 15:36:13 GMT 2023 , Edited by admin on Fri Dec 15 15:36:13 GMT 2023
Code System Code Type Description
CAS
5588-25-0
Created by admin on Fri Dec 15 15:36:13 GMT 2023 , Edited by admin on Fri Dec 15 15:36:13 GMT 2023
PRIMARY
PUBCHEM
21787
Created by admin on Fri Dec 15 15:36:13 GMT 2023 , Edited by admin on Fri Dec 15 15:36:13 GMT 2023
PRIMARY
EVMPD
SUB127444
Created by admin on Fri Dec 15 15:36:13 GMT 2023 , Edited by admin on Fri Dec 15 15:36:13 GMT 2023
PRIMARY
SMS_ID
100000153446
Created by admin on Fri Dec 15 15:36:13 GMT 2023 , Edited by admin on Fri Dec 15 15:36:13 GMT 2023
PRIMARY
ECHA (EC/EINECS)
226-996-9
Created by admin on Fri Dec 15 15:36:13 GMT 2023 , Edited by admin on Fri Dec 15 15:36:13 GMT 2023
PRIMARY
RXCUI
236210
Created by admin on Fri Dec 15 15:36:13 GMT 2023 , Edited by admin on Fri Dec 15 15:36:13 GMT 2023
PRIMARY RxNorm
FDA UNII
336704VYVB
Created by admin on Fri Dec 15 15:36:13 GMT 2023 , Edited by admin on Fri Dec 15 15:36:13 GMT 2023
PRIMARY
EPA CompTox
DTXSID00971286
Created by admin on Fri Dec 15 15:36:13 GMT 2023 , Edited by admin on Fri Dec 15 15:36:13 GMT 2023
PRIMARY
ChEMBL
CHEMBL2110912
Created by admin on Fri Dec 15 15:36:13 GMT 2023 , Edited by admin on Fri Dec 15 15:36:13 GMT 2023
PRIMARY
NCI_THESAURUS
C65386
Created by admin on Fri Dec 15 15:36:13 GMT 2023 , Edited by admin on Fri Dec 15 15:36:13 GMT 2023
PRIMARY
MERCK INDEX
m1114
Created by admin on Fri Dec 15 15:36:13 GMT 2023 , Edited by admin on Fri Dec 15 15:36:13 GMT 2023
PRIMARY Merck Index
ACTIVE MOIETY
Structure of DIHEXYVERINE
NIH
NCATS
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