Details
Stereochemistry | ACHIRAL |
Molecular Formula | Co |
Molecular Weight | 56.9363 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 2 |
SHOW SMILES / InChI
SMILES
[57Co++]
InChI
InChIKey=XLJKHNWPARRRJB-YPZZEJLDSA-N
InChI=1S/Co/q+2/i1-2
Cobaltous chloride CO-57 (or Cobalt 57) is a radioactive compound, decays by electron capture with a physical half-life of 270.9 days. This compound is a part of diagnostic capsules Rubratrope-57, for the diagnosis of pernicious anemia and as a diagnostic adjunct in other defects of intestinal vitamin B12 absorption. Rubratrope-57 was withdrawn in July 2017.
Approval Year
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Diagnostic | RUBRATOPE-57 Approved UseRubratope-57 (Cyanocobalamin Co 57 Capsules) is intended for the diagnosis of pernicious anemia and as a diagnostic adjunct in other defects of intestinal vitamin B12 absorption. Launch Date3.0499201E10 |
Sample Use Guides
In Vivo Use Guide
Sources: https://www.drugs.com/pro/rubratope-57.html
The suggested oral dose range for the average patient (70 kg)when performing a Schilling urinary excretion test is between 18.5 to 37 kBq (0.5 to 1 microcurie) of cyanocobalamin Co 57. The patient dose in each Cyanocobalamin Co 57 Capsule should be measured by a suitable radioacttivity calibration system immediately prior to administration.
Route of Administration:
Oral
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16256-07-8
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DTXSID80167408
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3141X260DR
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SALT/SOLVATE (PARENT)
SUBSTANCE RECORD