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Details

Stereochemistry ACHIRAL
Molecular Formula Co
Molecular Weight 56.936296235
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 2

SHOW SMILES / InChI
Structure of COBALTOUS CATION CO-57

SMILES

[57Co++]

InChI

InChIKey=XLJKHNWPARRRJB-YPZZEJLDSA-N
InChI=1S/Co/q+2/i1-2

HIDE SMILES / InChI

Molecular Formula Co
Molecular Weight 56.936296235
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Cobaltous chloride CO-57 (or Cobalt 57) is a radioactive compound, decays by electron capture with a physical half-life of 270.9 days. This compound is a part of diagnostic capsules Rubratrope-57, for the diagnosis of pernicious anemia and as a diagnostic adjunct in other defects of intestinal vitamin B12 absorption. Rubratrope-57 was withdrawn in July 2017.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
RUBRATOPE-57

Approved Use

Rubratope-57 (Cyanocobalamin Co 57 Capsules) is intended for the diagnosis of pernicious anemia and as a diagnostic adjunct in other defects of intestinal vitamin B12 absorption.

Launch Date

1970
PubMed

PubMed

TitleDatePubMed

Sample Use Guides

The suggested oral dose range for the average patient (70 kg)when performing a Schilling urinary excretion test is between 18.5 to 37 kBq (0.5 to 1 microcurie) of cyanocobalamin Co 57. The patient dose in each Cyanocobalamin Co 57 Capsule should be measured by a suitable radioacttivity calibration system immediately prior to administration.
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:01:47 GMT 2025
Edited
by admin
on Mon Mar 31 21:01:47 GMT 2025
Record UNII
3141X260DR
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
COBALTOUS CATION CO-57
Common Name English
57CO2+
Preferred Name English
COBALTOUS ION CO-57
Common Name English
COBALT-57 ION(2+)
Common Name English
COBALT, ISOTOPE OF MASS 57 (57CO2+)
Common Name English
Code System Code Type Description
PUBCHEM
71510781
Created by admin on Mon Mar 31 21:01:47 GMT 2025 , Edited by admin on Mon Mar 31 21:01:47 GMT 2025
PRIMARY
CAS
16256-07-8
Created by admin on Mon Mar 31 21:01:47 GMT 2025 , Edited by admin on Mon Mar 31 21:01:47 GMT 2025
PRIMARY
EPA CompTox
DTXSID80167408
Created by admin on Mon Mar 31 21:01:47 GMT 2025 , Edited by admin on Mon Mar 31 21:01:47 GMT 2025
PRIMARY
FDA UNII
3141X260DR
Created by admin on Mon Mar 31 21:01:47 GMT 2025 , Edited by admin on Mon Mar 31 21:01:47 GMT 2025
PRIMARY
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