Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H6O8S2 |
| Molecular Weight | 270.237 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC1=C(O)C(=CC(=C1)S(O)(=O)=O)S(O)(=O)=O
InChI
InChIKey=XXAXVMUWHZHZMJ-UHFFFAOYSA-N
InChI=1S/C6H6O8S2/c7-4-1-3(15(9,10)11)2-5(6(4)8)16(12,13)14/h1-2,7-8H,(H,9,10,11)(H,12,13,14)
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Ketoconazole induces apoptosis in rat cardiomyocytes through reactive oxygen species-mediated parkin overexpression. | 2015-10 |
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| Arsenic trioxide induces unfolded protein response in vascular endothelial cells. | 2014-02 |
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| Effect of resveratrol and tiron on the inactivation of glyceraldehyde-3- phosphate dehydrogenase induced by superoxide anion radical. | 2014 |
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| A synergistic vascular effect of airborne particulate matter and nickel in a mouse model. | 2013-09 |
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| ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons. | 2012-11-15 |
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| Melamine induces human renal proximal tubular cell injury via transforming growth factor-β and oxidative stress. | 2012-11 |
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| Upregulation of haeme oxygenase-1 by zinc in HCT-116 cells. | 2012-09 |
|
| Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation. | 2012-07-20 |
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| NADPH oxidase-produced superoxide mediates EGFR transactivation by c-Src in arsenic trioxide-stimulated human keratinocytes. | 2012-06 |
|
| Arsenic modulates heme oxygenase-1, interleukin-6, and vascular endothelial growth factor expression in endothelial cells: roles of ROS, NF-κB, and MAPK pathways. | 2012-06 |
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| Reactive oxygen species-dependent RhoA activation mediates collagen synthesis in hyperoxic lung fibrosis. | 2011-06-01 |
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| Cellular iron depletion weakens induction of heme oxygenase-1 by cadmium. | 2011-01 |
|
| Cyclosporine A-induced nitration of tyrosine 34 MnSOD in endothelial cells: role of mitochondrial superoxide. | 2010-07-15 |
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| Ursodeoxycholic acid switches oxaliplatin-induced necrosis to apoptosis by inhibiting reactive oxygen species production and activating p53-caspase 8 pathway in HepG2 hepatocellular carcinoma. | 2010-04-01 |
|
| Apigenin-induced apoptosis is mediated by reactive oxygen species and activation of ERK1/2 in rheumatoid fibroblast-like synoviocytes. | 2009-11-10 |
|
| N,N-dimethyl phytosphingosine induces caspase-8-dependent cytochrome c release and apoptosis through ROS generation in human leukemia cells. | 2009-08-15 |
|
| Acrolein activates matrix metalloproteinases by increasing reactive oxygen species in macrophages. | 2009-04-15 |
|
| p66Shc links alpha1-adrenergic receptors to a reactive oxygen species-dependent AKT-FOXO3A phosphorylation pathway in cardiomyocytes. | 2009-03-13 |
|
| Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species. | 2007-12-01 |
|
| NADPH oxidase mediates angiotensin II-induced endothelin-1 expression in vascular adventitial fibroblasts. | 2007-09-01 |
|
| Antioxidants tiron and N-acetyl-L-cysteine differentially mediate apoptosis in melanoma cells via a reactive oxygen species-independent NF-kappaB pathway. | 2007-05-01 |
|
| Induction of oxidative stress response by the mycotoxin patulin in mammalian cells. | 2007-02 |
|
| NAD(P)H oxidase activity of Nox4 in chondrocytes is both inducible and involved in collagenase expression. | 2006-09-22 |
|
| Participation of superoxide in neutrophil activation and cytokine production. | 2006-08 |
|
| Manganese modulates pro-inflammatory gene expression in activated glia. | 2006-07 |
|
| PS-341 (bortezomib) induces lysosomal cathepsin B release and a caspase-2-dependent mitochondrial permeabilization and apoptosis in human pancreatic cancer cells. | 2006-04-28 |
|
| Prolonged oxidative stress inverts the cardiac force-frequency relation: role of altered calcium handling and myofilament calcium responsiveness. | 2006-01 |
|
| Hyperglycemia activates JAK2 signaling pathway in human failing myocytes via angiotensin II-mediated oxidative stress. | 2005-02 |
|
| Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells. | 2004-11 |
|
| HSP25 overexpression attenuates oxidative stress-induced apoptosis: roles of ERK1/2 signaling and manganese superoxide dismutase. | 2004-02-15 |
|
| Melanoma differentiation associated gene-7, mda-7/interleukin-24, induces apoptosis in prostate cancer cells by promoting mitochondrial dysfunction and inducing reactive oxygen species. | 2003-12-01 |
|
| High glucose stimulates angiotensinogen gene expression via reactive oxygen species generation in rat kidney proximal tubular cells. | 2002-08 |
|
| Oxidative stress involves in astrocytic alterations induced by manganese. | 2002-05 |
|
| Antioxidant treatment induces transcription and expression of transforming growth factor beta in cultured renal proximal tubular cells. | 2001-01-19 |
|
| Hypoxia induces the expression of a 43-kDa protein (PROXY-1) in normal and malignant cells. | 2000-09-16 |
|
| Induction of superoxide dismutase and cytotoxicity by manganese in human breast cancer cells. | 1999-05-15 |
Patents
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| Code System | Code | Type | Description | ||
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306J0THJ9U
Created by
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9002
Created by
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DTXSID6043963
Created by
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205-742-0
Created by
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149-46-2
Created by
admin on Mon Mar 31 20:04:15 GMT 2025 , Edited by admin on Mon Mar 31 20:04:15 GMT 2025
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SALT/SOLVATE (PARENT)
SALT/SOLVATE (PARENT)
SUBSTANCE RECORD
