TIRON

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H4O8S2.2Na
Molecular Weight	314.201
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].[Na+].OC1=C(O)C(=CC(=C1)S([O-])(=O)=O)S([O-])(=O)=O

InChI

InChIKey=ISWQCIVKKSOKNN-UHFFFAOYSA-L

InChI=1S/C6H6O8S2.2Na/c7-4-1-3(15(9,10)11)2-5(6(4)8)16(12,13)14;;/h1-2,7-8H,(H,9,10,11)(H,12,13,14);;/q;2*+1/p-2

HIDE SMILES / InChI

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C6H4O8S2
Molecular Weight	268.221
Charge	-2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Oxidative stress involves in astrocytic alterations induced by manganese.	2002 May	12009774
Melanoma differentiation associated gene-7, mda-7/interleukin-24, induces apoptosis in prostate cancer cells by promoting mitochondrial dysfunction and inducing reactive oxygen species.	2003 Dec 1	14678967
Hyperglycemia activates JAK2 signaling pathway in human failing myocytes via angiotensin II-mediated oxidative stress.	2005 Feb	15677497
Manganese modulates pro-inflammatory gene expression in activated glia.	2006 Jul	16488514
Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species.	2007 Dec 1	18032788
NADPH oxidase-produced superoxide mediates EGFR transactivation by c-Src in arsenic trioxide-stimulated human keratinocytes.	2012 Jun	22532027
Arsenic modulates heme oxygenase-1, interleukin-6, and vascular endothelial growth factor expression in endothelial cells: roles of ROS, NF-κB, and MAPK pathways.	2012 Jun	22488045
A synergistic vascular effect of airborne particulate matter and nickel in a mouse model.	2013 Sep	23788629

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:57:06 GMT 2023` Edited by `admin` on `Fri Dec 15 17:57:06 GMT 2023`
Record UNII	4X87R5T106
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TIRON

Common Name

English

1,2-DIHYDROXYBENZENE-3,5-DISULFONIC ACID DISODIUM SALT

Common Name

English

SODIUM PYROCATECHOL-2,4-DISULFONATE

Systematic Name

English

DISODIUM-1,2-DIHYDROXYBENZENE-3,5-DISULFONATE

Systematic Name

English

NSC-12861

Code

English

4,5-DIHYDROXY-1,3-BENZENEDISULFONIC ACID DISODIUM SALT

Common Name

English

DISODIUM PYROCATECHOL-3,5-DISULFONATE

Systematic Name

English

TIRON [MI]

Common Name

English

SODIUM CATECHOL DISULFONATE

Systematic Name

English

Code System Code Type Description

FDA UNII

4X87R5T106