U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C4H11NO
Molecular Weight 89.1362
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DEANOL

SMILES

CN(C)CCO

InChI

InChIKey=UEEJHVSXFDXPFK-UHFFFAOYSA-N
InChI=1S/C4H11NO/c1-5(2)3-4-6/h6H,3-4H2,1-2H3

HIDE SMILES / InChI
DEANOL is an inactive component of CERAVE® hydrocortisone anti-itch cream, which is used for temporarily relieve itching associated with minor skin irritations, inflammation, and rashes due to eczema, soaps, detergents, cosmetics, seborrheic dermatitis, psoriasis. DEANOL is also used as a food additive.

Approval Year

Doses

Doses

DosePopulationAdverse events​
0.1 % single, topical
Highest studied dose
healthy
6000 mg 1 times / day multiple, oral
Highest studied dose
Dose: 6000 mg, 1 times / day
Route: oral
Route: multiple
Dose: 6000 mg, 1 times / day
Sources: Page: p.188
unhealthy
Health Status: unhealthy
Condition: Involuntary movement disorders
Sources: Page: p.188
Sourcing

Sourcing

Vendor/AggregatorIDURL
PubMed

PubMed

TitleDatePubMed
The relationship between the interfacial properties of surfactants and their toxicity to aquatic organisms.
2001 Mar 1
Split face study on the cutaneous tensile effect of 2-dimethylaminoethanol (deanol) gel.
2002 Aug
Preparation of phytate-removed deamidated soybean globulins by ion exchangers and characterization of their calcium-binding ability.
2002 Jan 2
[18F]fluoromethyl triflate, a novel and reactive [18F]fluoromethylating agent: preparation and application to the on-column preparation of [18F]fluorocholine.
2002 Sep
Reactivity and molecular recognition: amine methylation by an introverted ester.
2003 Dec 3
Efficacy of dimethylaminoethanol (DMAE) containing vitamin-mineral drug combination on EEG patterns in the presence of different emotional states.
2003 May 30
The sea urchin embryo as a model for mammalian developmental neurotoxicity: ontogenesis of the high-affinity choline transporter and its role in cholinergic trophic activity.
2003 Nov
[Fluorescent-labeled lipophilic analogues of serotonin, dopamine, and acetylcholine: synthesis, mass spectrometry, and biological activity].
2004 Sep-Oct
The role of dimethylaminoethanol in cosmetic dermatology.
2005
C-terminal sequencing method for proteins in polyacrylamide gel by the reaction of acetic anhydride.
2006 Apr
The evolution of senescence and post-reproductive lifespan in guppies (Poecilia reticulata).
2006 Jan
A new design strategy for dispersion stabilization of Ni particles based on the surface acid and base properties of Ni particles.
2007 Aug 15
Synthesis and characterization of succinylcholine-d18 and succinylmonocholine-d3 designed for simultaneous use as internal standards in mass spectrometric analyses.
2007 Jul
Improved automated synthesis of [18F]fluoroethylcholine as a radiotracer for cancer imaging.
2007 May 1
Mannosylated poly(ethylene oxide)-b-poly(epsilon-caprolactone) diblock copolymers: synthesis, characterization, and interaction with a bacterial lectin.
2007 Sep
Synthesis, cytotoxicity, DNA interaction, and topoisomerase II inhibition properties of novel indeno[2,1-c]quinolin-7-one and indeno[1,2-c]isoquinolin-5,11-dione derivatives.
2008 Jun 26
Quantitative determination of dimethylaminoethanol in cosmetic formulations by nuclear magnetic resonance spectroscopy.
2008 Nov-Dec
Mesotherapy - The french connection.
2010 Jan
The choC gene encoding a putative phospholipid methyltransferase is essential for growth and development in Aspergillus nidulans.
2010 Jun
Patents
Name Type Language
DEANOL
MART.   MI   WHO-DD  
Common Name English
N-(2-HYDROXYETHYL)-N,N-DIMETHYLAMINE
Systematic Name English
NSC-2652
Code English
N,N-DIMETHYL-2-HYDROXYETHYLAMINE
Systematic Name English
DIMETHYLETHANOLAMINE
Systematic Name English
ETHANOL, 2-(DIMETHYLAMINO)-
Systematic Name English
DIMETHYL MEA [INCI]
Common Name English
2-(DIMETHYLAMINO)ETHANOL
Systematic Name English
DIMETHYLAMINOETHANOL
Systematic Name English
N,N-DIMETHYLETHANOLAMINE
HSDB  
Systematic Name English
.BETA.-DIMETHYLAMINOETHYL ALCOHOL
Systematic Name English
Deanol [WHO-DD]
Common Name English
ORISTAR DMAE
Brand Name English
N,N-DIMETHYLETHANOLAMINE [HSDB]
Common Name English
DMAE
Common Name English
DEANOL [MART.]
Common Name English
DIMETHYL MEA
INCI  
INCI  
Official Name English
DEANOL [MI]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C265
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
DSLD 1303 (Number of products:461)
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
WHO-VATC QN06BX04
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
WHO-ATC N06BX04
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
Code System Code Type Description
NSC
2652
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
PRIMARY
SMS_ID
100000091061
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
PRIMARY
HSDB
1329
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
PRIMARY
DAILYMED
2N6K9DRA24
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
PRIMARY
MESH
D003642
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
PRIMARY
PUBCHEM
7902
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
PRIMARY
EVMPD
SUB13534MIG
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
PRIMARY
RXCUI
3116
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
PRIMARY RxNorm
CAS
108-01-0
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
PRIMARY
DRUG CENTRAL
787
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
PRIMARY
EPA CompTox
DTXSID2020505
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
PRIMARY
EVMPD
SUB13536MIG
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
ALTERNATIVE
WIKIPEDIA
DIMETHYLETHANOLAMINE
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
PRIMARY
CHEBI
271436
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
PRIMARY
DRUG BANK
DB13352
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
PRIMARY
NCI_THESAURUS
C72733
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
PRIMARY
FDA UNII
2N6K9DRA24
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
PRIMARY
MERCK INDEX
m4115
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
PRIMARY Merck Index
ECHA (EC/EINECS)
203-542-8
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
PRIMARY
MANUFACTURER PRODUCT INFORMATION
DEANOL
Created by admin on Fri Dec 15 14:58:34 GMT 2023 , Edited by admin on Fri Dec 15 14:58:34 GMT 2023
PRIMARY Dimethylethanolamine is used in the preparation of water-reducible coating formulations. Government regulations covering the amount of organic solvent allowable in the air have spurred a search for emission control procedures. One of the most promising is the replacement of the organic solvent by water. The resins used in coating formulations are not water soluble, but can be made so by reacting them with the amine.