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Details

Stereochemistry ACHIRAL
Molecular Formula C9H9NO3.C4H11NO
Molecular Weight 268.3089
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DEANOL ACETAMIDOBENZOATE

SMILES

CN(C)CCO.CC(=O)NC1=CC=C(C=C1)C(O)=O

InChI

InChIKey=XTWZHJXJIIUEJP-UHFFFAOYSA-N
InChI=1S/C9H9NO3.C4H11NO/c1-6(11)10-8-4-2-7(3-5-8)9(12)13;1-5(2)3-4-6/h2-5H,1H3,(H,10,11)(H,12,13);6H,3-4H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C4H11NO
Molecular Weight 89.1362
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C9H9NO3
Molecular Weight 179.1727
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

DEANOL is an inactive component of CERAVE® hydrocortisone anti-itch cream, which is used for temporarily relieve itching associated with minor skin irritations, inflammation, and rashes due to eczema, soaps, detergents, cosmetics, seborrheic dermatitis, psoriasis. DEANOL is also used as a food additive.

Approval Year

Doses

Doses

DosePopulationAdverse events​
0.1 % single, topical
Highest studied dose
healthy
6000 mg 1 times / day multiple, oral
Highest studied dose
Dose: 6000 mg, 1 times / day
Route: oral
Route: multiple
Dose: 6000 mg, 1 times / day
Sources: Page: p.188
unhealthy
Health Status: unhealthy
Condition: Involuntary movement disorders
Sources: Page: p.188
Sourcing

Sourcing

Vendor/AggregatorIDURL
PubMed

PubMed

TitleDatePubMed
Inhibitors of choline uptake and metabolism cause developmental abnormalities in neurulating mouse embryos.
2001 Aug
The relationship between the interfacial properties of surfactants and their toxicity to aquatic organisms.
2001 Mar 1
Improved method for the quality assurance of [C-11]choline.
2002 Apr
Perturbations in choline metabolism cause neural tube defects in mouse embryos in vitro.
2002 Apr
Preparation of phytate-removed deamidated soybean globulins by ion exchangers and characterization of their calcium-binding ability.
2002 Jan 2
Studies of the side chain cleavage of deramciclane in rats with radiolabelled compounds.
2002 Mar
[18F]fluoromethyl triflate, a novel and reactive [18F]fluoromethylating agent: preparation and application to the on-column preparation of [18F]fluorocholine.
2002 Sep
Water-soluble biodegradable cationic polyphosphazenes for gene delivery.
2003 May 20
Phosphazene-based ionic liquids: synthesis, temperature-dependent viscosity, and effect as additives in water lubrication of silicon nitride ceramics.
2004 Aug 23
[11C]Choline as a PET biomarker for assessment of prostate cancer tumor models.
2004 Jun 1
Copper (II)-mediated arylation with aryl boronic acids for the N-derivatization of pyrazole libraries.
2004 May-Jun
The role of dimethylaminoethanol in cosmetic dermatology.
2005
Synthesis of isostructural cage complexes of copper with cobalt and nickel for deposition of mixed ceramic oxide materials.
2006 Dec 25
The evolution of senescence and post-reproductive lifespan in guppies (Poecilia reticulata).
2006 Jan
Synthesis and characterization of succinylcholine-d18 and succinylmonocholine-d3 designed for simultaneous use as internal standards in mass spectrometric analyses.
2007 Jul
Improved automated synthesis of [18F]fluoroethylcholine as a radiotracer for cancer imaging.
2007 May 1
Randomised, placebo-controlled, double-blind, split-face study on the clinical efficacy of Tricutan on skin firmness.
2007 Nov
Synthesis, cytotoxicity, DNA interaction, and topoisomerase II inhibition properties of novel indeno[2,1-c]quinolin-7-one and indeno[1,2-c]isoquinolin-5,11-dione derivatives.
2008 Jun 26
Strong intramolecular Si-N interactions in the chlorosilanes Cl3-nHnSiOCH2CH2NMe2 (n = 1-3).
2008 Nov 17
Quantitative determination of dimethylaminoethanol in cosmetic formulations by nuclear magnetic resonance spectroscopy.
2008 Nov-Dec
In vivo skin effects of a dimethylaminoethanol (DMAE) based formulation.
2009 Dec
Effects of dimethylaminoethanol pyroglutamate (DMAE p-Glu) against memory deficits induced by scopolamine: evidence from preclinical and clinical studies.
2009 Dec
Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis.
2009 Jul
The pentameric vertex proteins are necessary for the icosahedral carboxysome shell to function as a CO2 leakage barrier.
2009 Oct 21
Application of high performance liquid chromatography coupled to on-line solid-phase extraction-nuclear magnetic resonance spectroscopy for the analysis of degradation products of V-class nerve agents and nitrogen mustard.
2010 Apr 23
First efficient synthesis of fluorinated glycidic esters from ketones.
2010 Feb 19
Mesotherapy - The french connection.
2010 Jan
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:03:49 UTC 2023
Edited
by admin
on Fri Dec 15 15:03:49 UTC 2023
Record UNII
JSQ17GL1CN
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DEANOL ACETAMIDOBENZOATE
MI   WHO-DD  
Common Name English
2-(DIMETHYLAMINO)ETHANOL P-ACETYLAMINOBENZOATE
Common Name English
DIMETHYLAMINOETHYL ACETAMIDOBENZOATE
Systematic Name English
BENZOIC ACID, 4-(ACETYLAMINO)-, COMPD. WITH 2-(DIMETHYLAMINO)ETHANOL (1:1)
Common Name English
DEANER
Brand Name English
NSC-97399
Code English
DEANOL ACETAMIDOBENZOATE [MI]
Common Name English
Deanol acetamidobenzoate [WHO-DD]
Common Name English
CERVOXAN
Brand Name English
ETHANOL, 2-(DIMETHYLAMINO)-, 4-(ACETYLAMINO)BENZOATE (SALT)
Common Name English
4-(ACETYLAMINO)BENZOIC ACID COMPD. WITH 2-(DIMETHYLAMINO)ETHANOL (1:1)
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C47795
Created by admin on Fri Dec 15 15:03:49 UTC 2023 , Edited by admin on Fri Dec 15 15:03:49 UTC 2023
Code System Code Type Description
NSC
97399
Created by admin on Fri Dec 15 15:03:49 UTC 2023 , Edited by admin on Fri Dec 15 15:03:49 UTC 2023
PRIMARY
CAS
3635-74-3
Created by admin on Fri Dec 15 15:03:49 UTC 2023 , Edited by admin on Fri Dec 15 15:03:49 UTC 2023
PRIMARY
EPA CompTox
DTXSID60189880
Created by admin on Fri Dec 15 15:03:49 UTC 2023 , Edited by admin on Fri Dec 15 15:03:49 UTC 2023
PRIMARY
RXCUI
22361
Created by admin on Fri Dec 15 15:03:49 UTC 2023 , Edited by admin on Fri Dec 15 15:03:49 UTC 2023
PRIMARY RxNorm
ECHA (EC/EINECS)
222-858-7
Created by admin on Fri Dec 15 15:03:49 UTC 2023 , Edited by admin on Fri Dec 15 15:03:49 UTC 2023
PRIMARY
MESH
C004777
Created by admin on Fri Dec 15 15:03:49 UTC 2023 , Edited by admin on Fri Dec 15 15:03:49 UTC 2023
PRIMARY
NCI_THESAURUS
C76621
Created by admin on Fri Dec 15 15:03:49 UTC 2023 , Edited by admin on Fri Dec 15 15:03:49 UTC 2023
PRIMARY
FDA UNII
JSQ17GL1CN
Created by admin on Fri Dec 15 15:03:49 UTC 2023 , Edited by admin on Fri Dec 15 15:03:49 UTC 2023
PRIMARY
EVMPD
SUB01558MIG
Created by admin on Fri Dec 15 15:03:49 UTC 2023 , Edited by admin on Fri Dec 15 15:03:49 UTC 2023
PRIMARY
PUBCHEM
19265
Created by admin on Fri Dec 15 15:03:49 UTC 2023 , Edited by admin on Fri Dec 15 15:03:49 UTC 2023
PRIMARY
SMS_ID
100000084678
Created by admin on Fri Dec 15 15:03:49 UTC 2023 , Edited by admin on Fri Dec 15 15:03:49 UTC 2023
PRIMARY
MERCK INDEX
m4115
Created by admin on Fri Dec 15 15:03:49 UTC 2023 , Edited by admin on Fri Dec 15 15:03:49 UTC 2023
PRIMARY Merck Index
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY