Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C5H7NO3.C4H11NO |
| Molecular Weight | 218.2502 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(C)CCO.OC(=O)[C@@H]1CCC(=O)N1
InChI
InChIKey=DAEHWWVKPWBXGD-DFWYDOINSA-N
InChI=1S/C5H7NO3.C4H11NO/c7-4-2-1-3(6-4)5(8)9;1-5(2)3-4-6/h3H,1-2H2,(H,6,7)(H,8,9);6H,3-4H2,1-2H3/t3-;/m0./s1
| Molecular Formula | C5H7NO3 |
| Molecular Weight | 129.114 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
| Molecular Formula | C4H11NO |
| Molecular Weight | 89.1362 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
DEANOL is an inactive component of CERAVE® hydrocortisone anti-itch cream, which is used for temporarily relieve itching associated with minor skin irritations, inflammation, and rashes due to eczema, soaps, detergents, cosmetics, seborrheic dermatitis, psoriasis. DEANOL is also used as a food additive.
Approval Year
Doses
| Dose | Population | Adverse events |
|---|---|---|
0.1 % single, topical Highest studied dose Dose: 0.1 % Route: topical Route: single Dose: 0.1 % Sources: Page: p.10 |
healthy Health Status: healthy Sources: Page: p.10 |
|
6000 mg 1 times / day multiple, oral Highest studied dose Dose: 6000 mg, 1 times / day Route: oral Route: multiple Dose: 6000 mg, 1 times / day Sources: Page: p.188 |
unhealthy Health Status: unhealthy Condition: Involuntary movement disorders Sources: Page: p.188 |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Perturbations in choline metabolism cause neural tube defects in mouse embryos in vitro. | 2002 Apr |
|
| Preparation of phytate-removed deamidated soybean globulins by ion exchangers and characterization of their calcium-binding ability. | 2002 Jan 2 |
|
| Studies of the side chain cleavage of deramciclane in rats with radiolabelled compounds. | 2002 Mar |
|
| [18F]fluoromethyl triflate, a novel and reactive [18F]fluoromethylating agent: preparation and application to the on-column preparation of [18F]fluorocholine. | 2002 Sep |
|
| Water-soluble biodegradable cationic polyphosphazenes for gene delivery. | 2003 May 20 |
|
| Efficacy of dimethylaminoethanol (DMAE) containing vitamin-mineral drug combination on EEG patterns in the presence of different emotional states. | 2003 May 30 |
|
| [11C]Choline as a PET biomarker for assessment of prostate cancer tumor models. | 2004 Jun 1 |
|
| Copper (II)-mediated arylation with aryl boronic acids for the N-derivatization of pyrazole libraries. | 2004 May-Jun |
|
| [Fluorescent-labeled lipophilic analogues of serotonin, dopamine, and acetylcholine: synthesis, mass spectrometry, and biological activity]. | 2004 Sep-Oct |
|
| The role of dimethylaminoethanol in cosmetic dermatology. | 2005 |
|
| C-terminal sequencing method for proteins in polyacrylamide gel by the reaction of acetic anhydride. | 2006 Apr |
|
| The evolution of senescence and post-reproductive lifespan in guppies (Poecilia reticulata). | 2006 Jan |
|
| A new design strategy for dispersion stabilization of Ni particles based on the surface acid and base properties of Ni particles. | 2007 Aug 15 |
|
| Self-assembly of the unique heterotrimetallic Cu/Co/M complexes possessing triangular antiferromagnetic {Cu2CoPb}2 and linear ferromagnetic {Cu2CoCd2} cores. | 2007 Feb 7 |
|
| Synthesis and characterization of succinylcholine-d18 and succinylmonocholine-d3 designed for simultaneous use as internal standards in mass spectrometric analyses. | 2007 Jul |
|
| Improved automated synthesis of [18F]fluoroethylcholine as a radiotracer for cancer imaging. | 2007 May 1 |
|
| Fully automated [18F]fluorocholine synthesis in the TracerLab MX FDG Coincidence synthesizer. | 2008 Feb |
|
| Experimental and theoretical investigation into the correlation between mass and ion mobility for choline and other ammonium cations in N2. | 2008 Mar 15 |
|
| Strong intramolecular Si-N interactions in the chlorosilanes Cl3-nHnSiOCH2CH2NMe2 (n = 1-3). | 2008 Nov 17 |
|
| Bis[N-(2-hydroxy-ethyl)-N-methyl-glycinato]copper(II). | 2008 Nov 22 |
|
| Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis. | 2009 Jul |
|
| Efficient automated one-step synthesis of 2-[18F]fluoroethylcholine for clinical imaging: optimized reaction conditions and improved quality controls of different synthetic approaches. | 2010 Apr |
|
| Application of high performance liquid chromatography coupled to on-line solid-phase extraction-nuclear magnetic resonance spectroscopy for the analysis of degradation products of V-class nerve agents and nitrogen mustard. | 2010 Apr 23 |
|
| First efficient synthesis of fluorinated glycidic esters from ketones. | 2010 Feb 19 |
|
| Structural characterization and stability of dimethylaminoethanol and dimethylaminoethanol bitartrate for possible use in cosmetic firming. | 2010 Jul-Aug |
|
| Chloridotris[μ(2)-2-(dimethyl-amino)-ethano-lato]-μ(3)-hydroxido-tri-μ(2)-trifluoro-acetato-tetra-copper(II) tetra-hydro-furan solvate. | 2010 Jun 18 |
|
| Release of DNA from polyelectrolyte multilayers fabricated using 'charge-shifting' cationic polymers: tunable temporal control and sequential, multi-agent release. | 2010 Nov 20 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
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Sat Dec 16 10:00:07 UTC 2023
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| Record UNII |
V68I8147P0
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Validated (UNII)
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ACTIVE MOIETY |