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Details

Stereochemistry ABSOLUTE
Molecular Formula C5H7NO3.C4H11NO
Molecular Weight 218.2502
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DEANOL PIDOLATE

SMILES

CN(C)CCO.OC(=O)[C@@H]1CCC(=O)N1

InChI

InChIKey=DAEHWWVKPWBXGD-DFWYDOINSA-N
InChI=1S/C5H7NO3.C4H11NO/c7-4-2-1-3(6-4)5(8)9;1-5(2)3-4-6/h3H,1-2H2,(H,6,7)(H,8,9);6H,3-4H2,1-2H3/t3-;/m0./s1

HIDE SMILES / InChI

Molecular Formula C5H7NO3
Molecular Weight 129.114
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula C4H11NO
Molecular Weight 89.1362
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

DEANOL is an inactive component of CERAVE® hydrocortisone anti-itch cream, which is used for temporarily relieve itching associated with minor skin irritations, inflammation, and rashes due to eczema, soaps, detergents, cosmetics, seborrheic dermatitis, psoriasis. DEANOL is also used as a food additive.

Approval Year

Doses

Doses

DosePopulationAdverse events​
0.1 % single, topical
Highest studied dose
healthy
6000 mg 1 times / day multiple, oral
Highest studied dose
Dose: 6000 mg, 1 times / day
Route: oral
Route: multiple
Dose: 6000 mg, 1 times / day
Sources: Page: p.188
unhealthy
Health Status: unhealthy
Condition: Involuntary movement disorders
Sources: Page: p.188
Sourcing

Sourcing

Vendor/AggregatorIDURL
PubMed

PubMed

TitleDatePubMed
Improved method for the quality assurance of [C-11]choline.
2002 Apr
Studies of the side chain cleavage of deramciclane in rats with radiolabelled compounds.
2002 Mar
[18F]fluoromethyl triflate, a novel and reactive [18F]fluoromethylating agent: preparation and application to the on-column preparation of [18F]fluorocholine.
2002 Sep
[Fluorescent-labeled lipophilic analogues of serotonin, dopamine, and acetylcholine: synthesis, mass spectrometry, and biological activity].
2004 Sep-Oct
The role of dimethylaminoethanol in cosmetic dermatology.
2005
The evolution of senescence and post-reproductive lifespan in guppies (Poecilia reticulata).
2006 Jan
Synthesis, cytotoxicity, DNA interaction, and topoisomerase II inhibition properties of novel indeno[2,1-c]quinolin-7-one and indeno[1,2-c]isoquinolin-5,11-dione derivatives.
2008 Jun 26
In vivo skin effects of a dimethylaminoethanol (DMAE) based formulation.
2009 Dec
Effects of dimethylaminoethanol pyroglutamate (DMAE p-Glu) against memory deficits induced by scopolamine: evidence from preclinical and clinical studies.
2009 Dec
The pentameric vertex proteins are necessary for the icosahedral carboxysome shell to function as a CO2 leakage barrier.
2009 Oct 21
Application of high performance liquid chromatography coupled to on-line solid-phase extraction-nuclear magnetic resonance spectroscopy for the analysis of degradation products of V-class nerve agents and nitrogen mustard.
2010 Apr 23
First efficient synthesis of fluorinated glycidic esters from ketones.
2010 Feb 19
Structural characterization and stability of dimethylaminoethanol and dimethylaminoethanol bitartrate for possible use in cosmetic firming.
2010 Jul-Aug
In vitro cytotoxicity of benzopyranone derivatives with basic side chain against human lung cell lines.
2010 Nov
Novel pathway to synthesize unsymmetrical 2,3,9,10,16,17,23-heptakis(alkoxyl)-24-mono(dimethylaminoalkoxyl)phthalocyanines.
2010 Oct 4
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 10:00:07 GMT 2023
Edited
by admin
on Sat Dec 16 10:00:07 GMT 2023
Record UNII
V68I8147P0
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DEANOL PIDOLATE
WHO-DD  
Common Name English
V-0191
Code English
ETHANOL, 2-(DIMETHYLAMINO)-, COMPD. WITH 5-OXO-L-PROLINE (1:1)
Systematic Name English
Deanol pidolate [WHO-DD]
Common Name English
DEANOL PYROGLUTAMATE
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID60946233
Created by admin on Sat Dec 16 10:00:07 GMT 2023 , Edited by admin on Sat Dec 16 10:00:07 GMT 2023
PRIMARY
CAS
23513-72-6
Created by admin on Sat Dec 16 10:00:07 GMT 2023 , Edited by admin on Sat Dec 16 10:00:07 GMT 2023
PRIMARY
EVMPD
SUB13537MIG
Created by admin on Sat Dec 16 10:00:07 GMT 2023 , Edited by admin on Sat Dec 16 10:00:07 GMT 2023
PRIMARY
PUBCHEM
71777631
Created by admin on Sat Dec 16 10:00:07 GMT 2023 , Edited by admin on Sat Dec 16 10:00:07 GMT 2023
PRIMARY
SMS_ID
100000079518
Created by admin on Sat Dec 16 10:00:07 GMT 2023 , Edited by admin on Sat Dec 16 10:00:07 GMT 2023
PRIMARY
RXCUI
236195
Created by admin on Sat Dec 16 10:00:07 GMT 2023 , Edited by admin on Sat Dec 16 10:00:07 GMT 2023
PRIMARY RxNorm
ECHA (EC/EINECS)
245-706-1
Created by admin on Sat Dec 16 10:00:07 GMT 2023 , Edited by admin on Sat Dec 16 10:00:07 GMT 2023
PRIMARY
FDA UNII
V68I8147P0
Created by admin on Sat Dec 16 10:00:07 GMT 2023 , Edited by admin on Sat Dec 16 10:00:07 GMT 2023
PRIMARY
EVMPD
SUB29994
Created by admin on Sat Dec 16 10:00:07 GMT 2023 , Edited by admin on Sat Dec 16 10:00:07 GMT 2023
PRIMARY
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