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Details

Stereochemistry ACHIRAL
Molecular Formula I.Na
Molecular Weight 145.89536722
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM IODIDE I-123

SMILES

[Na+].[123I-]

InChI

InChIKey=FVAUCKIRQBBSSJ-VVUPZWBASA-M
InChI=1S/HI.Na/h1H;/q;+1/p-1/i1-4;

HIDE SMILES / InChI

Description

Iodide ion I-123 is the most suitable isotope of iodine for the diagnostic study of thyroid diseases. Sodium Iodide I 131 Capsules Diagnostic is indicated for use in adults for: Assessment of thyroid function using radioactive iodine (RAI) uptake test and Imaging the thyroid (scintigraphy). The following adverse reaction has been described elsewhere in the labeling: Hypersensitivity Reactions. The following adverse reactions have been identified during post-approval use from Sodium Iodide I 131 Capsules Diagnostic: Gastrointestinal disorders (vomiting, nausea, and diarrhea); General disorders and administration site conditions (local thyroid swelling); Immune system disorders (hypersensitivity reactions); Skin and subcutaneous tissue disorders (itching, rash, hives, and erythema). Certain drugs and iodine-containing foods interfere with the accumulation of radioiodide by the thyroid.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
SODIUM IODIDE I 123

Sample Use Guides

In Vivo Use Guide
The recommended oral dose range for diagnostic studies of thyroid function in the average adult patient (70 kg) is 3.7-14.8 MBq (100-400 uCi) of Sodium Iodide I-123. The lower portion of the range 3.7 MBq (100 uCi) is recommended for uptake studies alone, and the higher portion 14.8 MBq (400 uCi) for thyroid imaging.
Route of Administration: Oral