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Details

Stereochemistry ACHIRAL
Molecular Formula I
Molecular Weight 122.905597944
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge -1

SHOW SMILES / InChI
Structure of IODIDE ION I-123

SMILES

[123I-]

InChI

InChIKey=XMBWDFGMSWQBCA-AHCXROLUSA-M
InChI=1S/HI/h1H/p-1/i1-4

HIDE SMILES / InChI

Molecular Formula HI
Molecular Weight 123.91354
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Iodide ion I-123 is the most suitable isotope of iodine for the diagnostic study of thyroid diseases. Sodium Iodide I 131 Capsules Diagnostic is indicated for use in adults for: Assessment of thyroid function using radioactive iodine (RAI) uptake test and Imaging the thyroid (scintigraphy). The following adverse reaction has been described elsewhere in the labeling: Hypersensitivity Reactions. The following adverse reactions have been identified during post-approval use from Sodium Iodide I 131 Capsules Diagnostic: Gastrointestinal disorders (vomiting, nausea, and diarrhea); General disorders and administration site conditions (local thyroid swelling); Immune system disorders (hypersensitivity reactions); Skin and subcutaneous tissue disorders (itching, rash, hives, and erythema). Certain drugs and iodine-containing foods interfere with the accumulation of radioiodide by the thyroid.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
SODIUM IODIDE I 123

Sample Use Guides

In Vivo Use Guide
The recommended oral dose range for diagnostic studies of thyroid function in the average adult patient (70 kg) is 3.7-14.8 MBq (100-400 uCi) of Sodium Iodide I-123. The lower portion of the range 3.7 MBq (100 uCi) is recommended for uptake studies alone, and the higher portion 14.8 MBq (400 uCi) for thyroid imaging.
Route of Administration: Oral
Substance Class Chemical
Record UNII
98QPV8670C
Record Status Validated (UNII)
Record Version