Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C7H10N2 |
| Molecular Weight | 122.1677 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=C(N)C=CC(N)=C1
InChI
InChIKey=OBCSAIDCZQSFQH-UHFFFAOYSA-N
InChI=1S/C7H10N2/c1-5-4-6(8)2-3-7(5)9/h2-4H,8-9H2,1H3
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Is benzoquinone the prohapten in cross-sensitivity among aminobenzene compounds? | 1998 Dec |
|
| The spectrum of allergic (cross-)sensitivity in clinical patch testing with 'para amino' compounds. | 2002 Apr |
|
| Hair dye-sensitized hairdressers: the cross-reaction pattern with new generation hair dyes. | 2002 Jun |
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| Comparative investigation of multiple organs of mice and rats in the comet assay. | 2002 May 27 |
|
| Contact allergy to ingredients of hair cosmetics in female hairdressers and clients--an 8-year analysis of IVDK data. | 2003 Nov |
|
| Thiol antioxidants block the activation of antigen-presenting cells by contact sensitizers. | 2003 Nov |
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| Hair dye contact allergy: quantitative exposure assessment of selected products and clinical cases. | 2004 Jun |
|
| Characterization of the sensitizing potential of chemicals by in vitro analysis of dendritic cell activation and skin penetration. | 2004 May |
|
| Occupational dermal exposure to permanent hair dyes among hairdressers. | 2005 Aug |
|
| Patch test reactions to cosmetic allergens in 1995-1997 and 2000-2002 in Finland--a multicentre study. | 2005 Jul |
|
| Different results of the Salmonella umu test between three isomers of phenylenediamine (PDA) derivatives. | 2006 |
|
| Unconsumed precursors and couplers after formation of oxidative hair dyes. | 2006 Aug |
|
| [The expanding role of occupational and non-occupational allergy to paraphenylenediamine]. | 2007 |
|
| Permeability of hair dye compounds p-phenylenediamine, toluene-2,5-diaminesulfate and resorcinol through protective gloves in hairdressing. | 2007 Jul |
|
| A clinical assessment of a patch test kit marketed to U.K. hairdressers for detecting hair dye allergy. | 2007 Nov |
|
| The reaction mechanism of p-toluenediamine anodic oxidation: an in situ ESR-UV/Vis/NIR spectroelectrochemical study. | 2007 Oct 8 |
|
| Allergic contact dermatitis from toluene-2,5-diamine in a cream dye for eyelashes and eyebrows--quantitative exposure assessment. | 2007 Sep |
|
| Toluene-2,5-diamine may be an isolated allergy in individuals sensitized by permanent hair dye. | 2007 Sep |
|
| Reactivity of in vitro activated human T lymphocytes to p-phenylenediamine and related substances. | 2008 Oct |
|
| [Determination of 22 components in hair dyes by high performance liquid chromatography]. | 2008 Sep |
|
| Primary sensitization to toluene-2,5-diamine giving rise to early positive patch reaction to p-phenylenediamine and late to toluene-2,5-diamine. | 2008 Sep |
|
| [Results of patch test in hairdressers examined in the institute of occupational medicine in Łódź]. | 2009 |
|
| Cross-reactions among hair dye allergens. | 2009 |
|
| Hairdye-induced hepatitis: an unusal cause of acute hepatitis. | 2009 Apr |
|
| Occupational health risks of barbers and coiffeurs in Izmir. | 2009 Aug |
|
| Metabolite screening of aromatic amine hair dyes using in vitro hepatic models. | 2009 Nov |
|
| Severe inflammatory and keloidal, allergic reaction due to para-phenylenediamine in temporary tattoos. | 2010 Mar-Apr |
|
| Final amended report of the safety assessment of toluene-2,5-diamine, toluene-2,5-diamine sulfate, and toluene-3,4-diamine as used in cosmetics. | 2010 May |
|
| Para-phenylenediamine-specific lymphocyte activation test: a sensitive in vitro assay to detect para-phenylenediamine sensitization in patients with severe allergic reactions. | 2010 May |
|
| Biological transformation pathways of 2,4-dinitro anisole and N-methyl paranitro aniline in anaerobic fluidized-bed bioreactors. | 2010 Nov |
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| Code System | Code | Type | Description | ||
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SUB169432
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DTXSID6029123
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100000159425
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C007303
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1482535
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24JO8Z0RJU
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7252
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53619
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2,5-DIAMINOTOLUENE
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6251
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95-70-5
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24JO8Z0RJU
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202-442-1
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ACTIVE MOIETY
SALT/SOLVATE (PARENT)
SALT/SOLVATE (PARENT)
