Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C7H10N2.2ClH |
| Molecular Weight | 195.09 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.Cl.CC1=CC(N)=CC=C1N
InChI
InChIKey=VQUHVWVGRKTIBH-UHFFFAOYSA-N
InChI=1S/C7H10N2.2ClH/c1-5-4-6(8)2-3-7(5)9;;/h2-4H,8-9H2,1H3;2*1H
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C7H10N2 |
| Molecular Weight | 122.1677 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Biological transformation pathways of 2,4-dinitro anisole and N-methyl paranitro aniline in anaerobic fluidized-bed bioreactors. | 2010-11 |
|
| Final amended report of the safety assessment of toluene-2,5-diamine, toluene-2,5-diamine sulfate, and toluene-3,4-diamine as used in cosmetics. | 2010-05 |
|
| Para-phenylenediamine-specific lymphocyte activation test: a sensitive in vitro assay to detect para-phenylenediamine sensitization in patients with severe allergic reactions. | 2010-05 |
|
| Severe inflammatory and keloidal, allergic reaction due to para-phenylenediamine in temporary tattoos. | 2010-03-16 |
|
| Metabolite screening of aromatic amine hair dyes using in vitro hepatic models. | 2009-11 |
|
| Occupational health risks of barbers and coiffeurs in Izmir. | 2009-08 |
|
| Hairdye-induced hepatitis: an unusal cause of acute hepatitis. | 2009-04 |
|
| [Results of patch test in hairdressers examined in the institute of occupational medicine in Łódź]. | 2009 |
|
| Cross-reactions among hair dye allergens. | 2009 |
|
| Reactivity of in vitro activated human T lymphocytes to p-phenylenediamine and related substances. | 2008-10 |
|
| [Determination of 22 components in hair dyes by high performance liquid chromatography]. | 2008-09 |
|
| Primary sensitization to toluene-2,5-diamine giving rise to early positive patch reaction to p-phenylenediamine and late to toluene-2,5-diamine. | 2008-09 |
|
| A clinical assessment of a patch test kit marketed to U.K. hairdressers for detecting hair dye allergy. | 2007-11 |
|
| The reaction mechanism of p-toluenediamine anodic oxidation: an in situ ESR-UV/Vis/NIR spectroelectrochemical study. | 2007-10-08 |
|
| Allergic contact dermatitis from toluene-2,5-diamine in a cream dye for eyelashes and eyebrows--quantitative exposure assessment. | 2007-09 |
|
| Toluene-2,5-diamine may be an isolated allergy in individuals sensitized by permanent hair dye. | 2007-09 |
|
| Permeability of hair dye compounds p-phenylenediamine, toluene-2,5-diaminesulfate and resorcinol through protective gloves in hairdressing. | 2007-07 |
|
| [The expanding role of occupational and non-occupational allergy to paraphenylenediamine]. | 2007 |
|
| Unconsumed precursors and couplers after formation of oxidative hair dyes. | 2006-08 |
|
| Different results of the Salmonella umu test between three isomers of phenylenediamine (PDA) derivatives. | 2006 |
|
| Occupational dermal exposure to permanent hair dyes among hairdressers. | 2005-08 |
|
| Patch test reactions to cosmetic allergens in 1995-1997 and 2000-2002 in Finland--a multicentre study. | 2005-07 |
|
| Hair dye contact allergy: quantitative exposure assessment of selected products and clinical cases. | 2004-06 |
|
| Characterization of the sensitizing potential of chemicals by in vitro analysis of dendritic cell activation and skin penetration. | 2004-05 |
|
| Contact allergy to ingredients of hair cosmetics in female hairdressers and clients--an 8-year analysis of IVDK data. | 2003-11 |
|
| Thiol antioxidants block the activation of antigen-presenting cells by contact sensitizers. | 2003-11 |
|
| Hair dye-sensitized hairdressers: the cross-reaction pattern with new generation hair dyes. | 2002-06 |
|
| Comparative investigation of multiple organs of mice and rats in the comet assay. | 2002-05-27 |
|
| The spectrum of allergic (cross-)sensitivity in clinical patch testing with 'para amino' compounds. | 2002-04 |
|
| Is benzoquinone the prohapten in cross-sensitivity among aminobenzene compounds? | 1998-12 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:01:08 GMT 2025
by
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on
Mon Mar 31 21:01:08 GMT 2025
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| Record UNII |
GY506235UT
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| Record Status |
Validated (UNII)
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| Record Version |
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615-45-2
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11996
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