Details
| Stereochemistry | RACEMIC |
| Molecular Formula | 2C5H9O3S.Ca |
| Molecular Weight | 338.454 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Ca++].CSCCC(O)C([O-])=O.CSCCC(O)C([O-])=O
InChI
InChIKey=ABRVDWASZFDIEH-UHFFFAOYSA-L
InChI=1S/2C5H10O3S.Ca/c2*1-9-3-2-4(6)5(7)8;/h2*4,6H,2-3H2,1H3,(H,7,8);/q;;+2/p-2
Desmeninol is a methionine hydroxyl analog. It is used as a feed additive for livestock, especially poultry to provide an essential amino acid necessary for the nutritional well being of farm raised animals. Desmeninol (ALIMET) has 88% methionine activity and is 100 percent absorbed by the animal. The benefits of ALIMET go beyond it being a methionine source, including: Antioxidant effect in the feed; Maintained performance during heat stress; Energy savings in the feed mill; Increased feed intake.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Effects of alimet on nutrient digestibility, bacterial protein synthesis, and ruminal disappearance during continuous culture. | 2001 Jan |
|
| Lactobacillus casei and Lactobacillus plantarum initiate catabolism of methionine by transamination. | 2001 Jun |
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| Effects of calcium salts of fatty acids and calcium salt of methionine hydroxy analogue on plasma prostaglandin F2alpha metabolite and milk fatty acid profiles in late lactation Holstein-Friesian cows. | 2002 Nov |
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| Effects of zinc and sodium monensin on ruminal degradation of lysine-HCl and liquid 2-hydroxy-4-methylthiobutanoic acid. | 2004 Aug |
|
| Estimation of bioavailability of DL-methionine hydroxy analogue relative to DL-methionine in layers with exponential and slope-ratio models. | 2004 Sep |
|
| The influence of dietary sodium chloride, arginine:lysine ratio, and methionine source on apparent ileal digestibility of arginine and lysine in acutely heat-stressed broilers. | 2005 Feb |
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| Metal chelates of 2-hydroxy-4-methylthiobutanoic acid in animal feeding. Part 2: Further characterizations, in vitro and in vivo investigations. | 2005 Feb |
|
| Determination of rumen degradability and ruminal effects of three sources of methionine in lactating cows. | 2005 Jan |
|
| Effects of 2-hydroxy-4-(methylthio) butanoic acid (HMB) and its isopropyl ester on milk production and composition by Holstein cows. | 2005 Jul |
|
| Estimation of the ideal ratio of true ileal digestible sulfur amino acids:lysine in 8- to 26-kg nursery pigs. | 2005 Nov |
|
| Methionine availability in plasma of dairy cows supplemented with methionine hydroxy analog isopropyl ester. | 2005 Oct |
|
| Comparative in vitro and in vivo absorption of 2-hydroxy-4(methylthio) butanoic acid and methionine in the broiler chicken. | 2005 Sep |
|
| The effects of various organic acids on phytate phosphorus utilization in chicks. | 2005 Sep |
|
| A multiple regression model approach to contrast the performance of 2-hydroxy-4-methylthio butanoic acid and DL-methionine supplementation tested in broiler experiments and reported in the literature. | 2006 Apr |
|
| Effects of dietary supplementation of DL-methionine or 2-hydroxy-4-(methylthio)-butanoic acid on food intake, nutrient digestibility, nitrogen balance, and urinary and blood metabolites in healthy, growing dogs. | 2006 Aug |
|
| Evidence for 2-hydroxy-4(methylthio) butanoic acid and DL-methionine having different dose responses in growing broilers. | 2006 Aug |
|
| Concentrations of putrescine, spermidine, and spermine in duodenum and pancreas as affected by the ratio of arginine to lysine and source of methionine in broilers under heat stress. | 2006 Aug |
|
| No evidence for different dose responses of commercial methionine sources in broilers. | 2006 Dec |
|
| Multidimensional chromatographic approach applied to the identification of novel aroma compounds in wine. Identification of ethyl cyclohexanoate, ethyl 2-hydroxy-3-methylbutyrate and ethyl 2-hydroxy-4-methylpentanoate. | 2006 Dec 29 |
|
| Oligomers are not the limiting factor in the absorption of DL-2-hydroxy-4-(methylthio)butanoic acid in the chicken small intestine. | 2006 Jan |
|
| Estimation of the true ileal digestible lysine and sulfur amino acid requirement and comparison of the bioefficacy of 2-hydroxy-4-(methylthio)butanoic acid and DL-methionine in eleven- to twenty-six-kilogram nursery pigs. | 2006 Jul |
|
| Absorption of 2-hydroxy-4-methylthiobutyrate and conversion to methionine in lambs. | 2006 Mar |
|
| Hepatic metabolism of 2-hydroxy-4-methylthiobutyrate in growing lambs. | 2006 Mar |
|
| Appropriate statistical methods to compare dose responses of methionine sources. | 2006 May |
|
| Effect of different forms of methionine on lactational performance of dairy cows. | 2006 Nov |
|
| Conversion of the methionine hydroxy analogue DL-2-hydroxy-(4-methylthio) butanoic acid to sulfur-containing amino acids in the chicken small intestine. | 2006 Nov |
|
| Homocysteine remethylation in broilers fed surfeit choline or betaine and varying levels and sources of methionine from eight to twenty-two days of age. | 2006 Oct |
|
| Absorption and digestive tract metabolism of 2-hydroxy-4-methylthiobutanoic acid in lambs. | 2006 Sep |
|
| Impact of feeding 2-hydroxy-4-(methylthio)butanoic acid and DL-methionine supplemented maize-soybean-rapeseed meal diets on growth performance and carcase quality of broilers. | 2007 Apr |
|
| Assessment of ruminal bacterial populations and protozoal generation time in cows fed different methionine sources. | 2007 Feb |
|
| Short communication: Absorption of 2-hydroxy-4-methylthiobutanoate in dairy cows. | 2007 Jun |
|
| Evidence of a different dose response in turkeys when fed 2-hydroxy-4(methylthio) butanoic acid versus DL-methionine. | 2007 Mar |
|
| Determining the methionine activity of Mintrex organic trace minerals in broiler chicks by using radiolabel tracing or growth assay. | 2007 May |
|
| Effects of rumen-undegradable protein sources and supplemental 2-hydroxy-4-(methylthio)-butanoic acid and lysine-HCl on lactation performance in dairy cows. | 2007 Nov |
|
| Effect of different dietary methionine sources on intestinal microbial populations in broiler chickens. | 2007 Nov |
|
| Effect of excess methionine and methionine hydroxy analogue on growth performance and plasma homocysteine of growing Pekin ducks. | 2007 Sep |
|
| The effect of several organic acids on phytate phosphorus hydrolysis in broiler chicks. | 2008 Apr |
|
| Effects of 2-hydroxy-4-(methylthio)-butanoic acid on performance and carcass characteristics of finishing beef cattle and on fermentation in continuous culture. | 2008 Aug |
|
| Partial Na+ dependence of DL-2-hydroxy-4-(methylthio)butanoic acid uptake in the chicken small intestine. | 2008 Jul |
|
| Effects of liquid DL-2-hydroxy-4-methylthio butanoic acid on growth performance and immune responses in broiler chickens. | 2008 Jul |
|
| Molecular analysis of microbial community structure in the chicken ileum following organic acid supplementation. | 2009 Jun 12 |
|
| Effects of 2-hydroxy-4-methylthiobutyrate on portal plasma flow and net portal appearance of amino acids in piglets. | 2009 Mar |
|
| Apparent absorption of methionine and 2-hydroxy-4-methylthiobutanoic acid from gastrointestinal tract of conventional and gnotobiotic pigs. | 2009 Oct |
|
| Effects of providing two forms of supplemental methionine to periparturient Holstein dairy cows on feed intake and lactational performance. | 2009 Oct |
|
| Effects of dietary supplementation of methionine and lysine on milk production and nitrogen utilization in dairy cows. | 2010 Aug |
|
| Short communication: transport of 2-hydroxy-4-methyl-thio-butanoic isopropyl ester by rumen epithelium in vitro. | 2010 Jan |
|
| Effects of adding liquid DL-methionine hydroxy analogue-free acid to drinking water on growth performance and small intestinal morphology of nursery pigs. | 2010 Jun |
|
| Effects of dl-2-hydroxy-4-methylthiobutyrate on the first-pass intestinal metabolism of dietary methionine and its extra-intestinal availability. | 2010 Mar |
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107344
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SUB124789
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1738094
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1VK0YS654L
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m7318
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PRIMARY | Merck Index |
ACTIVE MOIETY
SUBSTANCE RECORD
