DESMENINOL CALCIUM

Details

Stereochemistry	RACEMIC
Molecular Formula	2C5H9O3S.Ca
Molecular Weight	338.454
Optical Activity	( + / - )
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Ca++].CSCCC(O)C([O-])=O.CSCCC(O)C([O-])=O

InChI

InChIKey=ABRVDWASZFDIEH-UHFFFAOYSA-L

InChI=1S/2C5H10O3S.Ca/c2*1-9-3-2-4(6)5(7)8;/h2*4,6H,2-3H2,1H3,(H,7,8);/q;;+2/p-2

HIDE SMILES / InChI

Molecular Formula	C5H9O3S
Molecular Weight	149.188
Charge	-1
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Molecular Formula	Ca
Molecular Weight	40.078
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.novusint.com/Products/alimet | Milne, G.W.A. (2005) Gardner's Commercially Important Chemicals, page 182, retrieved from: https://books.google.ru/books?id=oWdc2qcb3QsC | Advice Concerning the Addition of Certain Pharmaceutical Products and Chemical Intermediates to the Pharmaceutical Appendix to the Harmonized Tariff Schedule of the United States, Inv. 332-476, page C-19, retrieved from: https://books.google.ru/books?id=ZbUM36IWbSIC

Desmeninol is a methionine hydroxyl analog. It is used as a feed additive for livestock, especially poultry to provide an essential amino acid necessary for the nutritional well being of farm raised animals. Desmeninol (ALIMET) has 88% methionine activity and is 100 percent absorbed by the animal. The benefits of ALIMET go beyond it being a methionine source, including: Antioxidant effect in the feed; Maintained performance during heat stress; Energy savings in the feed mill; Increased feed intake.

Approval Year

PubMed

Title	Date	PubMed
Uptake of DL-2-hydroxy-4-methylthio-butanoic acid (DL-HMB) in the broiler liver in vivo.	2001 Nov	11732679
[The feed value in growing pigs of a new cultivar of field beans (Vicia faba L.) supplemented with DL-methionine or DL-methionine-hydroxyanalog].	2002 Feb	11906570
Feeding 2-hydroxy-4-(methylthio)-butanoic acid to periparturient dairy cows improves milk production but not hepatic metabolism.	2004 Apr	15259243
Methionine availability in plasma of dairy cows supplemented with methionine hydroxy analog isopropyl ester.	2005 Oct	16162538
Effects of dietary supplementation of DL-methionine or 2-hydroxy-4-(methylthio)-butanoic acid on food intake, nutrient digestibility, nitrogen balance, and urinary and blood metabolites in healthy, growing dogs.	2006 Aug	16921927
No evidence for different dose responses of commercial methionine sources in broilers.	2006 Dec	17135657
Absorption of 2-hydroxy-4-methylthiobutyrate and conversion to methionine in lambs.	2006 Mar	16507704
Appropriate statistical methods to compare dose responses of methionine sources.	2006 May	16673777
Homocysteine remethylation in broilers fed surfeit choline or betaine and varying levels and sources of methionine from eight to twenty-two days of age.	2006 Oct	17012162
Impact of feeding 2-hydroxy-4-(methylthio)butanoic acid and DL-methionine supplemented maize-soybean-rapeseed meal diets on growth performance and carcase quality of broilers.	2007 Apr	17453811
Short communication: Absorption of 2-hydroxy-4-methylthiobutanoate in dairy cows.	2007 Jun	17517734
Effects of rumen-undegradable protein sources and supplemental 2-hydroxy-4-(methylthio)-butanoic acid and lysine-HCl on lactation performance in dairy cows.	2007 Nov	17954758
Effect of different dietary methionine sources on intestinal microbial populations in broiler chickens.	2007 Nov	17954586
Effect of excess methionine and methionine hydroxy analogue on growth performance and plasma homocysteine of growing Pekin ducks.	2007 Sep	17704389
The effect of several organic acids on phytate phosphorus hydrolysis in broiler chicks.	2008 Apr	18339989
Effects of dietary supplementation of methionine and lysine on milk production and nitrogen utilization in dairy cows.	2010 Aug	20655436
Effects of dl-2-hydroxy-4-methylthiobutyrate on the first-pass intestinal metabolism of dietary methionine and its extra-intestinal availability.	2010 Mar	20064283

Substance Class	Chemical Created by `admin` on `Sat Dec 16 05:50:35 GMT 2023` Edited by `admin` on `Sat Dec 16 05:50:35 GMT 2023`
Record UNII	1VK0YS654L
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DESMENINOL CALCIUM

Common Name

English

CALCIUM DL-.ALPHA.-HYDROXY-.GAMMA.-METHYLTHIOBUTYRATE

Common Name

English

CALCIUM HYDROXYMETHIONINE

Official Name

English

MHA

Brand Name

English

DL-METHIONINEHYDROXYANALOG CALCIUM

Common Name

English

CALCIUM BIS((1)-2-HYDROXY-4-(METHYLTHIO)BUTYRATE)

Common Name

English

Desmeninol Calcium [WHO-DD]

Common Name

English

BUTYRIC ACID, 2-HYDROXY-4-(METHYLTHIO)-, CALCIUM SALT (2:1)

Common Name

English

BUTANOIC ACID, 2-HYDROXY-4-(METHYLTHIO)-, CALCIUM SALT (2:1)

Common Name

English

(±)-DESMENINOL CALCIUM

Common Name

English

CALCIUM HYDROXYMETHIONINE [INCI]

Common Name

English

CALCIUM DESMENINOL

Common Name

English

METHIONINE HYDROXY ANALOG CALCIUM SALT [MI]

Common Name

English

CALCIUM DL-2-HYDROXY-4-METHYLTHIOBUTYRATE

Common Name

English

METHIONINE HYDROXY ANALOG-CALCIUM

Common Name

English

CALCIUM .ALPHA.-HYDROXY-.GAMMA.-METHYLMERCAPTOBUTYRATE

Systematic Name

English

NSC-1230

Code

English

HYDAN (METHIONINE HYDROXY ANALOG)

Common Name

English

Code System Code Type Description

NSC

1230