U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 2C12H13O4.Mg
Molecular Weight 466.7634
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 2
Charge 0

SHOW SMILES / InChI
Structure of DIMECROTATE MAGNESIUM

SMILES

[Mg++].COC1=CC=C(\C(C)=C/C([O-])=O)C(OC)=C1.COC2=CC=C(\C(C)=C/C([O-])=O)C(OC)=C2

InChI

InChIKey=NRMWCJKNPLZLMY-HIGYRTBYSA-L
InChI=1S/2C12H14O4.Mg/c2*1-8(6-12(13)14)10-5-4-9(15-2)7-11(10)16-3;/h2*4-7H,1-3H3,(H,13,14);/q;;+2/p-2/b2*8-6-;

HIDE SMILES / InChI
Dimecrotic acid is a choleretic agent with spasmolytic properties. It is obtained by reaction of resorcinol with acetoacetate to give 4-methyl-7-hydroxycoumarin. It is indicated for the treatment of hepato-digestive insufficiency and its manifestations. It shouldn’t be used in case of blockage of bile ducts, severe liver failure and severe renal impairment. Diarrhea may be associated with high doses of dimecrotic acid.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Hepadial

Approved Use

Indicated for the symptomatic treatment of dyspepsia, associated with functional abdominal pain
PubMed

PubMed

TitleDatePubMed
Molecular search of new active drugs against Toxoplasma gondii.
1999
Patents

Patents

Sample Use Guides

50 mg three times a day before meals
Route of Administration: Oral
In Vitro Use Guide
Unknown
Name Type Language
DIMECROTATE MAGNESIUM
Common Name English
FISIOBIL
Brand Name English
DIMECROTIC ACID MAGNESIUM SALT
MI   WHO-DD  
Common Name English
DIMECROTIC ACID MAGNESIUM SALT [MI]
Common Name English
MAGNESIUM CIS-3-(2,4-DIMETHOXYPHENYL)CROTONATE
Systematic Name English
DIMECROTIC ACID MAGNESIUM
Common Name English
HEPADIAL
Brand Name English
Dimecrotic acid magnesium salt [WHO-DD]
Common Name English
2-BUTENOIC ACID, 3-(2,4-DIMETHOXYPHENYL)-, MAGNESIUM SALT (2:1), (2Z)-
Systematic Name English
Code System Code Type Description
SMS_ID
100000087491
Created by admin on Sat Dec 16 08:36:56 GMT 2023 , Edited by admin on Sat Dec 16 08:36:56 GMT 2023
PRIMARY
RXCUI
236347
Created by admin on Sat Dec 16 08:36:56 GMT 2023 , Edited by admin on Sat Dec 16 08:36:56 GMT 2023
PRIMARY RxNorm
MERCK INDEX
m4496
Created by admin on Sat Dec 16 08:36:56 GMT 2023 , Edited by admin on Sat Dec 16 08:36:56 GMT 2023
PRIMARY Merck Index
FDA UNII
1IZ92DEM5B
Created by admin on Sat Dec 16 08:36:56 GMT 2023 , Edited by admin on Sat Dec 16 08:36:56 GMT 2023
PRIMARY
ECHA (EC/EINECS)
247-407-1
Created by admin on Sat Dec 16 08:36:56 GMT 2023 , Edited by admin on Sat Dec 16 08:36:56 GMT 2023
PRIMARY
PUBCHEM
6446007
Created by admin on Sat Dec 16 08:36:56 GMT 2023 , Edited by admin on Sat Dec 16 08:36:56 GMT 2023
PRIMARY
EVMPD
SUB01737MIG
Created by admin on Sat Dec 16 08:36:56 GMT 2023 , Edited by admin on Sat Dec 16 08:36:56 GMT 2023
PRIMARY
CAS
54283-65-7
Created by admin on Sat Dec 16 08:36:56 GMT 2023 , Edited by admin on Sat Dec 16 08:36:56 GMT 2023
PRIMARY
CAS
26011-83-6
Created by admin on Sat Dec 16 08:36:56 GMT 2023 , Edited by admin on Sat Dec 16 08:36:56 GMT 2023
NON-SPECIFIC STEREOCHEMISTRY