DIMECROTATE MAGNESIUM

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	2C12H13O4.Mg
Molecular Weight	466.7634
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	2
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Mg++].COC1=CC=C(\C(C)=C/C([O-])=O)C(OC)=C1.COC2=CC=C(\C(C)=C/C([O-])=O)C(OC)=C2

InChI

InChIKey=NRMWCJKNPLZLMY-HIGYRTBYSA-L

InChI=1S/2C12H14O4.Mg/c2*1-8(6-12(13)14)10-5-4-9(15-2)7-11(10)16-3;/h2*4-7H,1-3H3,(H,13,14);/q;;+2/p-2/b2*8-6-;

HIDE SMILES / InChI

Molecular Formula	C12H13O4
Molecular Weight	221.2292
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Molecular Formula	Mg
Molecular Weight	24.305
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: DOI: 10.1002/14356007.a12_143 | http://medic.vn/2013/12/hepadial | http://sante.journaldesfemmes.com/medicaments/hepadial-50-mg/medicament-68842670

Dimecrotic acid is a choleretic agent with spasmolytic properties. It is obtained by reaction of resorcinol with acetoacetate to give 4-methyl-7-hydroxycoumarin. It is indicated for the treatment of hepato-digestive insufficiency and its manifestations. It shouldn’t be used in case of blockage of bile ducts, severe liver failure and severe renal impairment. Diarrhea may be associated with high doses of dimecrotic acid.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Dyspepsia 11 Sources: http://sante.journaldesfemmes.com/medicaments/hepadial-50-mg/medicament-68842670	Palliative		Approved 8429	Hepadial Approved Use Indicated for the symptomatic treatment of dyspepsia, associated with functional abdominal pain

PubMed

Title	Date	PubMed
Molecular search of new active drugs against Toxoplasma gondii.	1999	10408126

Patents

Sample Use Guides

In Vivo Use Guide

50 mg three times a day before meals

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:36:56 GMT 2023` Edited by `admin` on `Sat Dec 16 08:36:56 GMT 2023`
Record UNII	1IZ92DEM5B
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DIMECROTATE MAGNESIUM

Common Name

English

FISIOBIL

Brand Name

English

DIMECROTIC ACID MAGNESIUM SALT

Common Name

English

DIMECROTIC ACID MAGNESIUM SALT [MI]

Common Name

English

MAGNESIUM CIS-3-(2,4-DIMETHOXYPHENYL)CROTONATE

Systematic Name

English

DIMECROTIC ACID MAGNESIUM

Common Name

English

HEPADIAL

Brand Name

English

Dimecrotic acid magnesium salt [WHO-DD]

Common Name

English

2-BUTENOIC ACID, 3-(2,4-DIMETHOXYPHENYL)-, MAGNESIUM SALT (2:1), (2Z)-

Systematic Name

English

Code System Code Type Description

SMS_ID

100000087491