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Details

Stereochemistry RACEMIC
Molecular Formula C23H29NO3.ClH
Molecular Weight 403.942
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PHENOPERIDINE HYDROCHLORIDE

SMILES

Cl.CCOC(=O)C1(CCN(CCC(O)C2=CC=CC=C2)CC1)C3=CC=CC=C3

InChI

InChIKey=HGEAGOBQOIMDQV-UHFFFAOYSA-N
InChI=1S/C23H29NO3.ClH/c1-2-27-22(26)23(20-11-7-4-8-12-20)14-17-24(18-15-23)16-13-21(25)19-9-5-3-6-10-19;/h3-12,21,25H,2,13-18H2,1H3;1H

HIDE SMILES / InChI

Description

PHENOPERIDINE is an opioid analgesic partly metabolized to meperidine in the liver. It is derived from pethidine by replacing the N methyl by a phenyl propanol chain. It is reputed to be a typical morphine-like analgesic characterized by its high potency, rapid onset of action, the intensity of its peak effect and the short duration of its pharmacological effects. It is used in general anesthesia.

Originator

Approval Year

Unknown
139594
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Approved
8429
Operidine

Approved Use

A narcotic analgesic
PubMed

PubMed

TitleDatePubMed
Contemporary strategies to preserve renal function during cardiac and vascular surgery.
2003
Patents

Patents

20040068222
2
Name Type Language
PHENOPERIDINE HYDROCHLORIDE
MI   WHO-DD  
Common Name English
OPERIDINE
Brand Name English
PHENOPERIDINE HYDROCHLORIDE [MI]
Common Name English
Phenoperidine hydrochloride [WHO-DD]
Common Name English
4-PIPERIDINECARBOXYLIC ACID, 1-(3-HYDROXY-3-PHENYLPROPYL)-4-PHENYL-, ETHYL ESTER, HYDROCHLORIDE (1:1)
Common Name English
ISONIPECOTIC ACID, 1-(3-HYDROXY-3-PHENYLPROPYL)-4-PHENYL-, ETHYL ESTER, HYDROCHLORIDE
Common Name English
4-PIPERIDINECARBOXYLIC ACID, 1-(3-HYDROXY-3-PHENYLPROPYL)-4-PHENYL-, ETHYL ESTER, HYDROCHLORIDE
Common Name English
LEALGIN
Brand Name English
PHENOPERIDINE HCL
Common Name English
Code System Code Type Description
CHEBI
31984
Created by admin on Fri Dec 15 15:03:47 GMT 2023 , Edited by admin on Fri Dec 15 15:03:47 GMT 2023
PRIMARY
SMS_ID
100000085293
Created by admin on Fri Dec 15 15:03:47 GMT 2023 , Edited by admin on Fri Dec 15 15:03:47 GMT 2023
PRIMARY
FDA UNII
1D9C1OK7KZ
Created by admin on Fri Dec 15 15:03:47 GMT 2023 , Edited by admin on Fri Dec 15 15:03:47 GMT 2023
PRIMARY
CAS
3627-49-4
Created by admin on Fri Dec 15 15:03:47 GMT 2023 , Edited by admin on Fri Dec 15 15:03:47 GMT 2023
PRIMARY
EVMPD
SUB03758MIG
Created by admin on Fri Dec 15 15:03:47 GMT 2023 , Edited by admin on Fri Dec 15 15:03:47 GMT 2023
PRIMARY
PUBCHEM
19260
Created by admin on Fri Dec 15 15:03:47 GMT 2023 , Edited by admin on Fri Dec 15 15:03:47 GMT 2023
PRIMARY
RXCUI
106508
Created by admin on Fri Dec 15 15:03:47 GMT 2023 , Edited by admin on Fri Dec 15 15:03:47 GMT 2023
PRIMARY RxNorm
ECHA (EC/EINECS)
222-846-1
Created by admin on Fri Dec 15 15:03:47 GMT 2023 , Edited by admin on Fri Dec 15 15:03:47 GMT 2023
PRIMARY
EPA CompTox
DTXSID10957657
Created by admin on Fri Dec 15 15:03:47 GMT 2023 , Edited by admin on Fri Dec 15 15:03:47 GMT 2023
PRIMARY
MERCK INDEX
m8632
Created by admin on Fri Dec 15 15:03:47 GMT 2023 , Edited by admin on Fri Dec 15 15:03:47 GMT 2023
PRIMARY Merck Index
PARENT (SALT/SOLVATE)
Structure of PHENOPERIDINE
NIH
NCATS
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