Details
Stereochemistry | RACEMIC |
Molecular Formula | C23H29NO3.ClH |
Molecular Weight | 403.942 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CCOC(=O)C1(CCN(CCC(O)C2=CC=CC=C2)CC1)C3=CC=CC=C3
InChI
InChIKey=HGEAGOBQOIMDQV-UHFFFAOYSA-N
InChI=1S/C23H29NO3.ClH/c1-2-27-22(26)23(20-11-7-4-8-12-20)14-17-24(18-15-23)16-13-21(25)19-9-5-3-6-10-19;/h3-12,21,25H,2,13-18H2,1H3;1H
PHENOPERIDINE is an opioid analgesic partly metabolized to meperidine in the liver. It is derived from pethidine by replacing the N methyl by a phenyl propanol chain. It is reputed to be a typical morphine-like analgesic characterized by its high potency, rapid onset of action, the intensity of its peak effect and the short duration of its pharmacological effects. It is used in general anesthesia.
Originator
Approval Year
PubMed
Title | Date | PubMed |
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Motor neuropathy associated with cimetidine. | 1980 Oct 11 |
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Contemporary strategies to preserve renal function during cardiac and vascular surgery. | 2003 |
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The consolidation of neuroleptic therapy: Janssen, the discovery of haloperidol and its introduction into clinical practice. | 2009 Apr 29 |
Patents
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31984
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100000085293
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1D9C1OK7KZ
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3627-49-4
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SUB03758MIG
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19260
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106508
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222-846-1
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DTXSID10957657
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m8632
Created by
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PRIMARY | Merck Index |
PARENT (SALT/SOLVATE)
SUBSTANCE RECORD