U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C15H13N3O4S
Molecular Weight 331.3481
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PIROXICAM

SMILES

CN1C(=C(c2ccccc2S1(=O)=O)O)C(=Nc3ccccn3)O

InChI

InChIKey=QYSPLQLAKJAUJT-UHFFFAOYSA-N
InChI=1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20)

HIDE SMILES / InChI

Description
Curator's Comment:: https://www.pfizermedicalinformation.com/en-us/feldene

Piroxicam is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). It was originally brought to market by Pfizer under the tradename Feldene in 1980, became generic in 1992, and is marketed worldwide under many brandnames. Piroxicam works by reducing hormones that cause inflammation and pain in the body. Piroxicam is used to reduce the pain, inflammation, and stiffness caused by rheumatoid arthritis and osteoarthritis. The antiinflammatory effect of Piroxicam may result from the reversible inhibition of cyclooxygenase, causing the peripheral inhibition of prostaglandin synthesis. The prostaglandins are produced by an enzyme called Cox-1. Piroxicam blocks the Cox-1 enzyme, resulting into the disruption of production of prostaglandins. Piroxicam also inhibits the migration of leukocytes into sites of inflammation and prevents the formation of thromboxane A2, an aggregating agent, by the platelets. Piroxicam is used for treatment of osteoarthritis and rheumatoid arthritis.

Originator

Curator's Comment:: originally brought to market by Pfizer under the tradename Feldene in 1980 # Pfizer

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: P04040
Gene ID: 847
Gene Symbol: CAT
Target Organism: Homo sapiens (Human)
0.413999999999999979 mM [IC50]
4.40000000000000036 µM [IC50]
Target ID: Aminopeptidase activity
70 µM [IC50]
73.7999999999999972 µM [IC50]
7 µM [IC50]
1.30000000000000004 µM [IC50]
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
FELDENE

Approved Use

FELDENE is a nonsteroidal anti-inflammatory drug indicated for Relief of the signs and symptoms of osteoarthritis (OA) Relief of the signs and symptoms of rheumatoid arthritis (RA)

Launch Date

386812800000
Primary
FELDENE

Approved Use

FELDENE is a nonsteroidal anti-inflammatory drug indicated for Relief of the signs and symptoms of osteoarthritis (OA) Relief of the signs and symptoms of rheumatoid arthritis (RA)

Launch Date

386812800000
Cmax

Cmax

ValueDoseCo-administeredAnalytePopulation
2.3 μg/mL
20 mg single, oral
dose: 20 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
PIROXICAM plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: MALE
food status: FASTED
AUC

AUC

ValueDoseCo-administeredAnalytePopulation
135.8 μg × h/mL
20 mg single, oral
dose: 20 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
PIROXICAM plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: MALE
food status: FASTED
T1/2

T1/2

ValueDoseCo-administeredAnalytePopulation
40.5 h
20 mg single, oral
dose: 20 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
PIROXICAM plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: MALE
food status: FASTED
Doses

Doses

DosePopulationAdverse events​
40 mg 1 times / day multiple, intramuscular
Highest studied dose
Dose: 40 mg, 1 times / day
Route: intramuscular
Route: multiple
Dose: 40 mg, 1 times / day
Sources:
unhealthy, 19 -74
Health Status: unhealthy
Age Group: 19 -74
Sex: M+F
Sources:
Disc. AE: Chest pain, Rash...
AEs leading to
discontinuation/dose reduction:
Chest pain (0.74%)
Rash (0.74%)
Vomiting (0.74%)
Exanthema (0.74%)
Injection site pain (0.74%)
Sources:
1800 mg single, oral
Overdose
Dose: 1800 mg
Route: oral
Route: single
Dose: 1800 mg
Sources:
unhealthy, 54
Health Status: unhealthy
Age Group: 54
Sex: F
Sources:
Disc. AE: Nausea, Abdominal pain...
AEs leading to
discontinuation/dose reduction:
Nausea
Abdominal pain
Gastric ulcer
Duodenal ulcer
Sources:
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy, 59.7+/-7.4
Health Status: unhealthy
Age Group: 59.7+/-7.4
Sex: M+F
Sources:
Disc. AE: Gastrointestinal disorders, Haemorrhage of digestive tract...
AEs leading to
discontinuation/dose reduction:
Gastrointestinal disorders (2.6%)
Haemorrhage of digestive tract (0.85%)
Headache (0.85%)
Oedema (0.85%)
Pruritus (0.85%)
Erythema facial (0.85%)
Sources:
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy, >40
Health Status: unhealthy
Age Group: >40
Sex: M+F
Sources:
Disc. AE: Epigastric discomfort, Diarrhoea...
AEs leading to
discontinuation/dose reduction:
Epigastric discomfort (2.5%)
Diarrhoea (2.5%)
Loose stools (2.5%)
Sources:
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy
Disc. AE: Cardiac thrombosis, Myocardial infarction...
AEs leading to
discontinuation/dose reduction:
Cardiac thrombosis (grade 3-5)
Myocardial infarction (grade 3-5)
Stroke (grade 3-5)
Gastrointestinal disorder NOS (serious)
Bleeding (serious)
Ulceration (serious)
Perforation stomach (grade 3-5)
Perforation of intestine (grade 3-5)
Sources:
AEs

AEs

AESignificanceDosePopulation
Chest pain 0.74%
Disc. AE
40 mg 1 times / day multiple, intramuscular
Highest studied dose
Dose: 40 mg, 1 times / day
Route: intramuscular
Route: multiple
Dose: 40 mg, 1 times / day
Sources:
unhealthy, 19 -74
Health Status: unhealthy
Age Group: 19 -74
Sex: M+F
Sources:
Exanthema 0.74%
Disc. AE
40 mg 1 times / day multiple, intramuscular
Highest studied dose
Dose: 40 mg, 1 times / day
Route: intramuscular
Route: multiple
Dose: 40 mg, 1 times / day
Sources:
unhealthy, 19 -74
Health Status: unhealthy
Age Group: 19 -74
Sex: M+F
Sources:
Injection site pain 0.74%
Disc. AE
40 mg 1 times / day multiple, intramuscular
Highest studied dose
Dose: 40 mg, 1 times / day
Route: intramuscular
Route: multiple
Dose: 40 mg, 1 times / day
Sources:
unhealthy, 19 -74
Health Status: unhealthy
Age Group: 19 -74
Sex: M+F
Sources:
Rash 0.74%
Disc. AE
40 mg 1 times / day multiple, intramuscular
Highest studied dose
Dose: 40 mg, 1 times / day
Route: intramuscular
Route: multiple
Dose: 40 mg, 1 times / day
Sources:
unhealthy, 19 -74
Health Status: unhealthy
Age Group: 19 -74
Sex: M+F
Sources:
Vomiting 0.74%
Disc. AE
40 mg 1 times / day multiple, intramuscular
Highest studied dose
Dose: 40 mg, 1 times / day
Route: intramuscular
Route: multiple
Dose: 40 mg, 1 times / day
Sources:
unhealthy, 19 -74
Health Status: unhealthy
Age Group: 19 -74
Sex: M+F
Sources:
Abdominal pain Disc. AE
1800 mg single, oral
Overdose
Dose: 1800 mg
Route: oral
Route: single
Dose: 1800 mg
Sources:
unhealthy, 54
Health Status: unhealthy
Age Group: 54
Sex: F
Sources:
Duodenal ulcer Disc. AE
1800 mg single, oral
Overdose
Dose: 1800 mg
Route: oral
Route: single
Dose: 1800 mg
Sources:
unhealthy, 54
Health Status: unhealthy
Age Group: 54
Sex: F
Sources:
Gastric ulcer Disc. AE
1800 mg single, oral
Overdose
Dose: 1800 mg
Route: oral
Route: single
Dose: 1800 mg
Sources:
unhealthy, 54
Health Status: unhealthy
Age Group: 54
Sex: F
Sources:
Nausea Disc. AE
1800 mg single, oral
Overdose
Dose: 1800 mg
Route: oral
Route: single
Dose: 1800 mg
Sources:
unhealthy, 54
Health Status: unhealthy
Age Group: 54
Sex: F
Sources:
Erythema facial 0.85%
Disc. AE
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy, 59.7+/-7.4
Health Status: unhealthy
Age Group: 59.7+/-7.4
Sex: M+F
Sources:
Haemorrhage of digestive tract 0.85%
Disc. AE
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy, 59.7+/-7.4
Health Status: unhealthy
Age Group: 59.7+/-7.4
Sex: M+F
Sources:
Headache 0.85%
Disc. AE
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy, 59.7+/-7.4
Health Status: unhealthy
Age Group: 59.7+/-7.4
Sex: M+F
Sources:
Oedema 0.85%
Disc. AE
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy, 59.7+/-7.4
Health Status: unhealthy
Age Group: 59.7+/-7.4
Sex: M+F
Sources:
Pruritus 0.85%
Disc. AE
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy, 59.7+/-7.4
Health Status: unhealthy
Age Group: 59.7+/-7.4
Sex: M+F
Sources:
Gastrointestinal disorders 2.6%
Disc. AE
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy, 59.7+/-7.4
Health Status: unhealthy
Age Group: 59.7+/-7.4
Sex: M+F
Sources:
Diarrhoea 2.5%
Disc. AE
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy, >40
Health Status: unhealthy
Age Group: >40
Sex: M+F
Sources:
Epigastric discomfort 2.5%
Disc. AE
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy, >40
Health Status: unhealthy
Age Group: >40
Sex: M+F
Sources:
Loose stools 2.5%
Disc. AE
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy, >40
Health Status: unhealthy
Age Group: >40
Sex: M+F
Sources:
Cardiac thrombosis grade 3-5
Disc. AE
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy
Myocardial infarction grade 3-5
Disc. AE
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy
Perforation of intestine grade 3-5
Disc. AE
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy
Perforation stomach grade 3-5
Disc. AE
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy
Stroke grade 3-5
Disc. AE
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy
Bleeding serious
Disc. AE
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy
Gastrointestinal disorder NOS serious
Disc. AE
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy
Ulceration serious
Disc. AE
20 mg 1 times / day multiple, oral
Recommended
Dose: 20 mg, 1 times / day
Route: oral
Route: multiple
Dose: 20 mg, 1 times / day
Sources:
unhealthy
Overview

Overview

OverviewOther

Other InhibitorOther SubstrateOther Inducer





Drug as perpetrator​

Drug as perpetrator​

Drug as victim

Drug as victim

TargetModalityActivityMetaboliteClinical evidence
major
yes (pharmacogenomic study)
Comment: Higher systemic exposure of piroxicam has been noted in subjects with CYP2C9 polymorphisms compared to normal metabolizer type subject
yes
Tox targets

Tox targets

PubMed

PubMed

TitleDatePubMed
Piroxicam-induced renal failure and hyperkalemia.
1983 Jul
Piroxicam-induced renal failure.
1983 Nov
Piroxicam-induced renal disease.
1984 Jan
Piroxicam-induced acute interstitial nephritis and minimal-change nephrotic syndrome.
1985
An interaction between lithium carbonate and piroxicam presenting as lithium toxicity.
1985 Aug
Piroxicam-induced acute renal failure (anuria)
1985 May
A double-blind multicentre trial of piroxicam and naproxen in osteoarthritis.
1986 Jan
Piroxicam in acute musculoskeletal disorders and sport injuries.
1987
[Fatal autoimmune hemolytic anemia probably induced by treatment with piroxicam].
1988 Mar 7
[Acute hemolytic anemia and hepatonephritis caused by piroxicam].
1988 Oct-Dec
Piroxicam-induced renal failure following relief of chronic retention.
1989 Apr
Severe cholestatic jaundice associated with piroxicam.
1991 Dec
Aplastic anaemia associated with piroxicam.
1991 Feb
A comparison of tenoxicam and piroxicam in the treatment of rheumatoid arthritis.
1992 Apr
[Iatrogenic axonal neuropathy and erythroderma induced by piroxicam. Manifestations of hypersensitivity?].
1993
Nonsteroidal antiinflammatory drugs and certain rare, serious adverse events: a cohort study.
1993 May-Jun
Anti-inflammatory effects of etodolac: comparison with other non-steroidal anti-inflammatory drugs.
1994 Dec
Comparison of ketorolac tromethamine with other injectable nonsteroidal anti-inflammatory drugs for pain-on-injection and muscle damage in the rat.
1994 Feb
Mechanism of anti-inflammatory action of fepradinol.
1994 Jan
Fetal renal maldevelopment with oligohydramnios following maternal use of piroxicam.
1994 Oct
Tenidap in rheumatoid arthritis. A 24-week double-blind comparison with hydroxychloroquine-plus-piroxicam, and piroxicam alone.
1995 Oct
Antiinflammatory 4,5-diarylpyrroles. 2. Activity as a function of cyclooxygenase-2 inhibition.
1995 Sep 29
Differential effects of nonsteroidal anti-inflammatory drugs on constitutive and inducible prostaglandin G/H synthase in cultured bone cells.
1997 Aug
Tenidap inhibits replication of the human immunodeficiency virus-1 in cultured cells.
1997 Jan 1
Effect of structural modification of enol-carboxamide-type nonsteroidal antiinflammatory drugs on COX-2/COX-1 selectivity.
1997 Mar 14
Piroxicam and acarbose as chemopreventive agents for spontaneous intestinal adenomas in APC gene 1309 knockout mice.
1998 Apr
Nonsteroidal anti-inflammatory drugs enhance glutathione S-transferase theta levels in rat colon.
1998 Aug 24
[Cholestatic hepatitis associated with piroxicam use. Case report].
1998 May
Identification of HIV-1 integrase inhibitors based on a four-point pharmacophore.
1998 Nov
Effects of celecoxib on acid-challenged gastric mucosa of rats: comparison with metamizol and piroxicam.
2004 Jun
Mechanisms of protection by pantoprazole against NSAID-induced gastric mucosal damage.
2005 Jul
Apoptotic efficacy and inhibitory effect of dexamethasone on matrix metalloproteinase.
2005 Jul
Comparison of developmental toxicity of selective and non-selective cyclooxygenase-2 inhibitors in CRL:(WI)WUBR Wistar rats--DFU and piroxicam study.
2005 Jul 1
Lansoprazole prevents experimental gastric injury induced by non-steroidal anti-inflammatory drugs through a reduction of mucosal oxidative damage.
2005 Jul 14
Oral aspirin challenges in patients with a history of intolerance to single non-steroidal anti-inflammatory drugs.
2005 Jun
Chemoprevention: mouse colon and lung tumor bioassay and modulation of DNA methylation as a biomarker.
2005 Mar
Translational studies on aromatase, cyclooxygenases, and enzyme inhibitors in breast cancer.
2005 May
The effects of L-748706, a selective cyclooxygenase-2 inhibitor, on N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis.
2005 Sep
Inhibition of human phenol and estrogen sulfotransferase by certain non-steroidal anti-inflammatory agents.
2006 Oct
Genetic susceptibility to nonsteroidal anti-inflammatory drug-related gastroduodenal bleeding: role of cytochrome P450 2C9 polymorphisms.
2007 Aug
Immunomodulatory effect of nonsteroidal anti-inflammatory drugs (NSAIDs) at the clinically available doses.
2007 Jan
In silico prediction of pregnane X receptor activators by machine learning approaches.
2007 Jan
Effect of acetaminophen, a cyclooxygenase inhibitor, on Morris water maze task performance in mice.
2007 Sep
Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration.
2009
Lack of effect of naltrindole on the spinal synergism of morphine and non-steroidal anti-inflammatory drugs (NSAIDS).
2009 Jun
Effects of cyclooxygenase inhibitor treatment on the renal toxicity of cisplatin in rats.
2010 Feb
The effect of non-steroidal anti-inflammatory agents on behavioural changes and cytokine production following systemic inflammation: Implications for a role of COX-1.
2010 Mar
Apoptosis induced by piroxicam plus cisplatin combined treatment is triggered by p21 in mesothelioma.
2011
Lung fibrosis induced by crystalline silica particles is uncoupled from lung inflammation in NMRI mice.
2011 Jun 10
Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.
2015 May 18
Patents

Sample Use Guides

Recommended dose: 20 mg orally once a day
Route of Administration: Oral
Contractions induced by bradykinin in guinea-pig gallbladder smooth muscle strips were significantly attenuated by the cyclooxygenase inhibitor piroxicam (10 muM).
Name Type Language
PIROXICAM
EP   INN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
INN   USAN  
Official Name English
4-HYDROXY-2-METHYL-N-2-PYRIDINYL-2H-1,2-BENZOTHIAZINE-3-CARBOXAMIDE 1,1-DIOXIDE
Systematic Name English
PIROXICAM [INN]
Common Name English
PIROXICAM [MI]
Common Name English
FELDENE
Brand Name English
PIROXICAM [EP MONOGRAPH]
Common Name English
NSC-666076
Code English
PIROXICAM [JAN]
Common Name English
PIROXICAM [USP-RS]
Common Name English
2H-1,2-BENZOTHIAZINE-3-CARBOXAMIDE, 4-HYDROXY-2-METHYL-N-2-PYRIDINYL-, 1,1-DIOXIDE
Systematic Name English
CP-16171
Code English
PIROXICAM [VANDF]
Common Name English
PIROXICAM [WHO-DD]
Common Name English
PIROXICAM ANHYDROUS
Common Name English
CP-16,171
Code English
PIROXICAM [USP MONOGRAPH]
Common Name English
PIROXICAM [USAN]
Common Name English
PIROXICAM [MART.]
Common Name English
PIROXICAM [ORANGE BOOK]
Common Name English
Classification Tree Code System Code
WHO-VATC QM01AC01
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
WHO-VATC QS01BC06
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
NDF-RT N0000175722
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
WHO-ATC S01BC06
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
NCI_THESAURUS C1915
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
NCI_THESAURUS C1323
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
WHO-ATC M01AC01
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
WHO-ATC M02AA07
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
NDF-RT N0000000160
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
NDF-RT N0000175721
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
WHO-VATC QM02AA07
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
LIVERTOX 782
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
Code System Code Type Description
DRUG CENTRAL
2210
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
PRIMARY
DRUG BANK
DB00554
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
PRIMARY
FDA UNII
13T4O6VMAM
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
PRIMARY
RXCUI
8356
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
PRIMARY
MERCK INDEX
M8889
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
PRIMARY Merck Index
EPA CompTox
36322-90-4
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
PRIMARY
CAS
36322-90-4
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
PRIMARY
IUPHAR
7273
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
PRIMARY
ECHA (EC/EINECS)
252-974-3
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
PRIMARY
USP_CATALOG
1544508
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
PRIMARY USP-RS
PUBCHEM
54676228
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
PRIMARY
RXCUI
68115
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
ALTERNATIVE
EVMPD
SUB127114
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
PRIMARY
LACTMED
Piroxicam
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
PRIMARY
EVMPD
SUB09936MIG
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
PRIMARY
WIKIPEDIA
PIROXICAM
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
PRIMARY
INN
3713
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
PRIMARY
ChEMBL
CHEMBL527
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
PRIMARY
NCI_THESAURUS
C751
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
PRIMARY
MESH
D010894
Created by admin on Fri Jun 25 20:57:29 UTC 2021 , Edited by admin on Fri Jun 25 20:57:29 UTC 2021
PRIMARY