Details
Stereochemistry | ACHIRAL |
Molecular Formula | C17H18Br2N4O2.2C2H6O4S |
Molecular Weight | 722.422 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
OCCS(O)(=O)=O.OCCS(O)(=O)=O.NC(=N)C1=CC=C(OCCCOC2=C(Br)C=C(C=C2)C(N)=N)C(Br)=C1
InChI
InChIKey=VFDASNWZZRLEAU-UHFFFAOYSA-N
InChI=1S/C17H18Br2N4O2.2C2H6O4S/c18-12-8-10(16(20)21)2-4-14(12)24-6-1-7-25-15-5-3-11(17(22)23)9-13(15)19;2*3-1-2-7(4,5)6/h2-5,8-9H,1,6-7H2,(H3,20,21)(H3,22,23);2*3H,1-2H2,(H,4,5,6)
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/4358232Curator's Comment: Description was created based on several sources, including http://www.goldeneyecare.co.uk/assets/Uploads/D52491-TP-GEOPL-UK-14v4-GoldenEye-Ointment-0.15.pdf | https://www.medicines.org.uk/emc/PIL.16474.latest.pdf
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4358232
Curator's Comment: Description was created based on several sources, including http://www.goldeneyecare.co.uk/assets/Uploads/D52491-TP-GEOPL-UK-14v4-GoldenEye-Ointment-0.15.pdf | https://www.medicines.org.uk/emc/PIL.16474.latest.pdf
Dibrompropamidine isetionate is an antiseptic.
Ointment containing dibrompropamidine isetionate is used to treat minor eye or eyelid infections, such as conjunctivitis and blepharitis.
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Studies on the mode of action of dibromopropamidine. | 1973 Jun-Aug |
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In vitro effect of diamidines on intracellular polyamines of Acanthamoeba polyphaga. | 2001 |
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Good visual outcome after prompt treatment of acanthamoeba keratitis associated with overnight orthokeratology lens wear. | 2007 Nov |
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Acanthamoeba keratitis: 2007: a train wreck in slow motion. | 2007 Sep |
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[When the treatment is the problem]. | 2009 Feb 12 |
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[Graze with unusual progress]. | 2009 Feb 12 |
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Cosmetic contact lens-related Acanthamoeba keratitis. | 2009 May |
Sample Use Guides
Eye ointment containing dibrompropamidine isethionate 0.15% w/w to the affected eye once or twice each day for at least 2 days
Route of Administration:
Topical
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4358232
Dibrompropamidine isethionate, 300 μg/ml in aqueous solution was rapidly bactericidal, killing 99.9% of E. coli 15 TAU cells in 3 min.
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210-399-5
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16735405
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100000092617
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SUB01662MIG
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22862
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614-87-9
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m4299
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12Y597MO62
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C053597
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DTXSID30210332
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528031
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33424
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ACTIVE MOIETY
PARENT (SALT/SOLVATE)
SUBSTANCE RECORD