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Details

Stereochemistry ACHIRAL
Molecular Formula C17H18Br2N4O2
Molecular Weight 470.158
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIBROMPROPAMIDINE

SMILES

NC(=N)C1=CC(Br)=C(OCCCOC2=C(Br)C=C(C=C2)C(N)=N)C=C1

InChI

InChIKey=GMJFVGRUYJHMCO-UHFFFAOYSA-N
InChI=1S/C17H18Br2N4O2/c18-12-8-10(16(20)21)2-4-14(12)24-6-1-7-25-15-5-3-11(17(22)23)9-13(15)19/h2-5,8-9H,1,6-7H2,(H3,20,21)(H3,22,23)

HIDE SMILES / InChI
Molecular Formula C17H18Br2N4O2
Molecular Weight 470.158
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Dibrompropamidine isetionate is an antiseptic. Ointment containing dibrompropamidine isetionate is used to treat minor eye or eyelid infections, such as conjunctivitis and blepharitis.

Approval Year

Unknown
149,124

Targets

Primary TargetPharmacologyConditionPotency
http://purl.obolibrary.org/obo/OMIT_0002795
3
Inhibitor
8,504

Conditions

ConditionModalityTargetsHighest PhaseProduct
Eye infections
13
 Curative
Approved
8,583
BROLENE

PubMed

Sample Use Guides

In Vivo Use Guide
Eye ointment containing dibrompropamidine isethionate 0.15% w/w to the affected eye once or twice each day for at least 2 days
Route of Administration: Topical
In Vitro Use Guide
Dibrompropamidine isethionate, 300 μg/ml in aqueous solution was rapidly bactericidal, killing 99.9% of E. coli 15 TAU cells in 3 min.
Substance Class Chemical
Record UNII
269M3QL74S
Record Status Validated (UNII)
Record Version
NIH
NCATS
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