Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C14H21N2O3.Na |
| Molecular Weight | 288.3179 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].CCCCC1C(=O)[N-]C(=O)N(C2CCCCC2)C1=O
InChI
InChIKey=SGESMFOVCAMYRA-UHFFFAOYSA-M
InChI=1S/C14H22N2O3.Na/c1-2-3-9-11-12(17)15-14(19)16(13(11)18)10-7-5-4-6-8-10;/h10-11H,2-9H2,1H3,(H,15,17,19);/q;+1/p-1
DescriptionCurator's Comment: Description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/18445991 and http://www.genome.jp/dbget-bin/www_bget?drug+D01661
Curator's Comment: Description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/18445991 and http://www.genome.jp/dbget-bin/www_bget?drug+D01661
Bucolome (Paramidine) is a barbiturate derivative. It is a non-steroidal anti-inflammatory drug, which is used in the treatment of chronic articular rheumatism. It has been used as a uricosuric and/or anti-inflammatory agent in Japan since 1967. Bucolome acts as a CYP2C9 inhibitor and reduces the metabolism of several commonly used drugs, which makes it useful for potentiating or extending the duration of action of those drugs, or reducing the production of unwanted metabolites.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| [Intraluminal ureteral hematoma complicating anticoagulant therapy]. | 2005-07 |
|
| Bucolome, a potent binding inhibitor for furosemide, alters the pharmacokinetics and diuretic effect of furosemide: potential for use of bucolome to restore diuretic response in nephrotic syndrome. | 2005-04 |
Patents
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Preferred Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
0QN61326HC
Created by
admin on Mon Mar 31 23:31:38 GMT 2025 , Edited by admin on Mon Mar 31 23:31:38 GMT 2025
|
PRIMARY | |||
|
23670498
Created by
admin on Mon Mar 31 23:31:38 GMT 2025 , Edited by admin on Mon Mar 31 23:31:38 GMT 2025
|
PRIMARY | |||
|
6891-28-7
Created by
admin on Mon Mar 31 23:31:38 GMT 2025 , Edited by admin on Mon Mar 31 23:31:38 GMT 2025
|
PRIMARY | |||
|
DTXSID30988620
Created by
admin on Mon Mar 31 23:31:38 GMT 2025 , Edited by admin on Mon Mar 31 23:31:38 GMT 2025
|
PRIMARY |
ACTIVE MOIETY
SUBSTANCE RECORD
