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Details

Stereochemistry ABSOLUTE
Molecular Formula C19H30O2
Molecular Weight 290.4403
Optical Activity UNSPECIFIED
Defined Stereocenters 7 / 7
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ANDROSTANOLONE

SMILES

[H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]3([H])[C@@]2([H])CC[C@@]4([H])CC(=O)CC[C@]34C

InChI

InChIKey=NVKAWKQGWWIWPM-ABEVXSGRSA-N
InChI=1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1

HIDE SMILES / InChI

Description

STANOLONE, also known as dihydrotestosterone, is a potent androgenic metabolite of testosterone and anabolic agent for systemic use. It may be used as a replacement of male sex steroids in men who have androgen deficiency, for example as a result of the loss of both testes, and also the treatment of certain rare forms of aplastic anemia which are or may be responsive to anabolic androgens.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Neodrol

Cmax

ValueDoseCo-administeredAnalytePopulation
7.8 nM
16 mg single, topical
STANOLONE serum
Homo sapiens

AUC

ValueDoseCo-administeredAnalytePopulation
44.8 nM × h
16 mg single, topical
STANOLONE serum
Homo sapiens

T1/2

ValueDoseCo-administeredAnalytePopulation
12 day
16 mg single, topical
STANOLONE serum
Homo sapiens

Funbound

ValueDoseCo-administeredAnalytePopulation
2%
unknown, unknown
STANOLONE plasma
Homo sapiens

Doses

Drug as perpetrator​

Drug as victim

Tox targets

PubMed