U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C16H26N2O2.ClH
Molecular Weight 314.851
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AMYDRICAINE HYDROCHLORIDE

SMILES

Cl.CCC(CN(C)C)(CN(C)C)OC(=O)C1=CC=CC=C1

InChI

InChIKey=FHHDPMSYDYZLAP-UHFFFAOYSA-N
InChI=1S/C16H26N2O2.ClH/c1-6-16(12-17(2)3,13-18(4)5)20-15(19)14-10-8-7-9-11-14;/h7-11H,6,12-13H2,1-5H3;1H

HIDE SMILES / InChI

Approval Year

Doses

Doses

DosePopulationAdverse events​
2 % 1 times / day single, intraurethral
Recommended
Dose: 2 %, 1 times / day
Route: intraurethral
Route: single
Dose: 2 %, 1 times / day
Sources:
unhealthy, adult
n = 2
Health Status: unhealthy
Age Group: adult
Sex: M
Population Size: 2
Sources:
Other AEs: Spasms, Cyanosis...
Other AEs:
Spasms
Cyanosis
Respiration spontaneous decreased
Sources:
10 % 1 times / day single, intraurethral
Studied dose
Dose: 10 %, 1 times / day
Route: intraurethral
Route: single
Dose: 10 %, 1 times / day
Sources:
healthy, adult
n = 3
Health Status: healthy
Age Group: adult
Sex: M
Population Size: 3
Sources:
Other AEs: Generalised convulsion, Respiration spontaneous decreased...
Other AEs:
Generalised convulsion
Respiration spontaneous decreased
Cyanosis
Sources:
AEs

AEs

AESignificanceDosePopulation
Cyanosis
2 % 1 times / day single, intraurethral
Recommended
Dose: 2 %, 1 times / day
Route: intraurethral
Route: single
Dose: 2 %, 1 times / day
Sources:
unhealthy, adult
n = 2
Health Status: unhealthy
Age Group: adult
Sex: M
Population Size: 2
Sources:
Respiration spontaneous decreased
2 % 1 times / day single, intraurethral
Recommended
Dose: 2 %, 1 times / day
Route: intraurethral
Route: single
Dose: 2 %, 1 times / day
Sources:
unhealthy, adult
n = 2
Health Status: unhealthy
Age Group: adult
Sex: M
Population Size: 2
Sources:
Spasms
2 % 1 times / day single, intraurethral
Recommended
Dose: 2 %, 1 times / day
Route: intraurethral
Route: single
Dose: 2 %, 1 times / day
Sources:
unhealthy, adult
n = 2
Health Status: unhealthy
Age Group: adult
Sex: M
Population Size: 2
Sources:
Cyanosis
10 % 1 times / day single, intraurethral
Studied dose
Dose: 10 %, 1 times / day
Route: intraurethral
Route: single
Dose: 10 %, 1 times / day
Sources:
healthy, adult
n = 3
Health Status: healthy
Age Group: adult
Sex: M
Population Size: 3
Sources:
Generalised convulsion
10 % 1 times / day single, intraurethral
Studied dose
Dose: 10 %, 1 times / day
Route: intraurethral
Route: single
Dose: 10 %, 1 times / day
Sources:
healthy, adult
n = 3
Health Status: healthy
Age Group: adult
Sex: M
Population Size: 3
Sources:
Respiration spontaneous decreased
10 % 1 times / day single, intraurethral
Studied dose
Dose: 10 %, 1 times / day
Route: intraurethral
Route: single
Dose: 10 %, 1 times / day
Sources:
healthy, adult
n = 3
Health Status: healthy
Age Group: adult
Sex: M
Population Size: 3
Sources:
Name Type Language
AMYDRICAINE HYDROCHLORIDE
Common Name English
AMYDRICAINE MONOHYDROCHLORIDE
Common Name English
2-BUTANOL, 1-(DIMETHYLAMINO)-2-((DIMETHYLAMINO)METHYL)-, BENZOATE, HYDROCHLORIDE
Systematic Name English
2-BUTANOL, 1-(DIMETHYLAMINO)-2-((DIMETHYLAMINO)METHYL)-, BENZOATE (ESTER), MONOHYDROCHLORIDE
Systematic Name English
2-BUTANOL, 1-(DIMETHYLAMINO)-2-((DIMETHYLAMINO)METHYL)-, BENZOATE (ESTER), HYDROCHLORIDE
Common Name English
ALIPINE
Brand Name English
ALYPIN HYDROCHLORIDE
Common Name English
2-BUTANOL, 1-(DIMETHYLAMINO)-2-((DIMETHYLAMINO)METHYL)-, 2-BENZOATE, HYDROCHLORIDE (1:1)
Systematic Name English
Code System Code Type Description
CAS
631-38-9
Created by admin on Sat Dec 16 09:42:20 GMT 2023 , Edited by admin on Sat Dec 16 09:42:20 GMT 2023
PRIMARY
FDA UNII
06F0ZZ018S
Created by admin on Sat Dec 16 09:42:20 GMT 2023 , Edited by admin on Sat Dec 16 09:42:20 GMT 2023
PRIMARY
ECHA (EC/EINECS)
211-156-6
Created by admin on Sat Dec 16 09:42:20 GMT 2023 , Edited by admin on Sat Dec 16 09:42:20 GMT 2023
PRIMARY
CAS
74195-82-7
Created by admin on Sat Dec 16 09:42:20 GMT 2023 , Edited by admin on Sat Dec 16 09:42:20 GMT 2023
NON-SPECIFIC STOICHIOMETRY
PUBCHEM
12427
Created by admin on Sat Dec 16 09:42:20 GMT 2023 , Edited by admin on Sat Dec 16 09:42:20 GMT 2023
PRIMARY