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Details

Stereochemistry ACHIRAL
Molecular Formula C16H26N2O2.ClH
Molecular Weight 314.851
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AMYDRICAINE HYDROCHLORIDE

SMILES

Cl.CCC(CN(C)C)(CN(C)C)OC(=O)C1=CC=CC=C1

InChI

InChIKey=FHHDPMSYDYZLAP-UHFFFAOYSA-N
InChI=1S/C16H26N2O2.ClH/c1-6-16(12-17(2)3,13-18(4)5)20-15(19)14-10-8-7-9-11-14;/h7-11H,6,12-13H2,1-5H3;1H

HIDE SMILES / InChI
Molecular Formula C16H26N2O2
Molecular Weight 278.3898
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

1905
13
Doses

Doses

DosePopulationAdverse events​
2 % 1 times / day single, intraurethral
Recommended
Dose: 2 %, 1 times / day
Route: intraurethral
Route: single
Dose: 2 %, 1 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/18737364/
unhealthy, adult
n = 2
Health Status: unhealthy
Age Group: adult
Sex: M
Population Size: 2
Sources:
https://pubmed.ncbi.nlm.nih.gov/18737364/
Other AEs: Spasms, Cyanosis...
Other AEs:
Spasms
Cyanosis
Respiration spontaneous decreased
Sources:
https://pubmed.ncbi.nlm.nih.gov/18737364/
10 % 1 times / day single, intraurethral
Studied dose
Dose: 10 %, 1 times / day
Route: intraurethral
Route: single
Dose: 10 %, 1 times / day
Sources:
https://jamanetwork.com/journals/jama/article-abstract/453290
healthy, adult
n = 3
Health Status: healthy
Age Group: adult
Sex: M
Population Size: 3
Sources:
https://jamanetwork.com/journals/jama/article-abstract/453290
Other AEs: Generalised convulsion, Respiration spontaneous decreased...
Other AEs:
Generalised convulsion
Respiration spontaneous decreased
Cyanosis
Sources:
https://jamanetwork.com/journals/jama/article-abstract/453290
AEs

AEs

AESignificanceDosePopulation
Cyanosis
2 % 1 times / day single, intraurethral
Recommended
Dose: 2 %, 1 times / day
Route: intraurethral
Route: single
Dose: 2 %, 1 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/18737364/
unhealthy, adult
n = 2
Health Status: unhealthy
Age Group: adult
Sex: M
Population Size: 2
Sources:
https://pubmed.ncbi.nlm.nih.gov/18737364/
Respiration spontaneous decreased
2 % 1 times / day single, intraurethral
Recommended
Dose: 2 %, 1 times / day
Route: intraurethral
Route: single
Dose: 2 %, 1 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/18737364/
unhealthy, adult
n = 2
Health Status: unhealthy
Age Group: adult
Sex: M
Population Size: 2
Sources:
https://pubmed.ncbi.nlm.nih.gov/18737364/
Spasms
2 % 1 times / day single, intraurethral
Recommended
Dose: 2 %, 1 times / day
Route: intraurethral
Route: single
Dose: 2 %, 1 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/18737364/
unhealthy, adult
n = 2
Health Status: unhealthy
Age Group: adult
Sex: M
Population Size: 2
Sources:
https://pubmed.ncbi.nlm.nih.gov/18737364/
Cyanosis
10 % 1 times / day single, intraurethral
Studied dose
Dose: 10 %, 1 times / day
Route: intraurethral
Route: single
Dose: 10 %, 1 times / day
Sources:
https://jamanetwork.com/journals/jama/article-abstract/453290
healthy, adult
n = 3
Health Status: healthy
Age Group: adult
Sex: M
Population Size: 3
Sources:
https://jamanetwork.com/journals/jama/article-abstract/453290
Generalised convulsion
10 % 1 times / day single, intraurethral
Studied dose
Dose: 10 %, 1 times / day
Route: intraurethral
Route: single
Dose: 10 %, 1 times / day
Sources:
https://jamanetwork.com/journals/jama/article-abstract/453290
healthy, adult
n = 3
Health Status: healthy
Age Group: adult
Sex: M
Population Size: 3
Sources:
https://jamanetwork.com/journals/jama/article-abstract/453290
Respiration spontaneous decreased
10 % 1 times / day single, intraurethral
Studied dose
Dose: 10 %, 1 times / day
Route: intraurethral
Route: single
Dose: 10 %, 1 times / day
Sources:
https://jamanetwork.com/journals/jama/article-abstract/453290
healthy, adult
n = 3
Health Status: healthy
Age Group: adult
Sex: M
Population Size: 3
Sources:
https://jamanetwork.com/journals/jama/article-abstract/453290
Sourcing

Sourcing

Vendor/AggregatorIDURL
ABI Chem
AC1L1ZKO
ChemMol
99178506
http://www.chemmol.com/chemmol/99178506.html
ChemTik
CTK5H8665
Chemieliva Pharmaceutical Co., Ltd
PBCM1028265
NovoSeek
12428
PubChem
12428
https://pubchem.ncbi.nlm.nih.gov/compound/12428
Smolecule
S518842
http://www.smolecule.com/products/s518842
THE BioTek
bt-259885
https://www.thebiotek.com/product/inhibitors/bt-259885
eNovation Chemicals
K79446
https://www.enovationchem.com/ProductDetails.asp?ProductID=K79446
Substance Class Chemical
Created
by admin
on Sat Dec 16 09:42:20 GMT 2023
Edited
by admin
on Sat Dec 16 09:42:20 GMT 2023
Record UNII
06F0ZZ018S
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AMYDRICAINE HYDROCHLORIDE
Common Name English
AMYDRICAINE MONOHYDROCHLORIDE
Common Name English
2-BUTANOL, 1-(DIMETHYLAMINO)-2-((DIMETHYLAMINO)METHYL)-, BENZOATE, HYDROCHLORIDE
Systematic Name English
2-BUTANOL, 1-(DIMETHYLAMINO)-2-((DIMETHYLAMINO)METHYL)-, BENZOATE (ESTER), MONOHYDROCHLORIDE
Systematic Name English
2-BUTANOL, 1-(DIMETHYLAMINO)-2-((DIMETHYLAMINO)METHYL)-, BENZOATE (ESTER), HYDROCHLORIDE
Common Name English
ALIPINE
Brand Name English
ALYPIN HYDROCHLORIDE
Common Name English
2-BUTANOL, 1-(DIMETHYLAMINO)-2-((DIMETHYLAMINO)METHYL)-, 2-BENZOATE, HYDROCHLORIDE (1:1)
Systematic Name English
Code System Code Type Description
CAS
631-38-9
Created by admin on Sat Dec 16 09:42:20 GMT 2023 , Edited by admin on Sat Dec 16 09:42:20 GMT 2023
PRIMARY
FDA UNII
06F0ZZ018S
Created by admin on Sat Dec 16 09:42:20 GMT 2023 , Edited by admin on Sat Dec 16 09:42:20 GMT 2023
PRIMARY
ECHA (EC/EINECS)
211-156-6
Created by admin on Sat Dec 16 09:42:20 GMT 2023 , Edited by admin on Sat Dec 16 09:42:20 GMT 2023
PRIMARY
CAS
74195-82-7
Created by admin on Sat Dec 16 09:42:20 GMT 2023 , Edited by admin on Sat Dec 16 09:42:20 GMT 2023
NON-SPECIFIC STOICHIOMETRY
PUBCHEM
12427
Created by admin on Sat Dec 16 09:42:20 GMT 2023 , Edited by admin on Sat Dec 16 09:42:20 GMT 2023
PRIMARY
Related Record Type Details
Structure of AMYDRICAINE
ACTIVE MOIETY
NIH
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