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Details

Stereochemistry ACHIRAL
Molecular Formula C16H26N2O2
Molecular Weight 278.3898
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AMYDRICAINE

SMILES

CCC(CN(C)C)(CN(C)C)OC(=O)C1=CC=CC=C1

InChI

InChIKey=VEXNFKCQMGMBBJ-UHFFFAOYSA-N
InChI=1S/C16H26N2O2/c1-6-16(12-17(2)3,13-18(4)5)20-15(19)14-10-8-7-9-11-14/h7-11H,6,12-13H2,1-5H3

HIDE SMILES / InChI
Molecular Formula C16H26N2O2
Molecular Weight 278.3898
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

1905
13
Doses

Doses

DosePopulationAdverse events​
2 % 1 times / day single, intraurethral
Recommended
Dose: 2 %, 1 times / day
Route: intraurethral
Route: single
Dose: 2 %, 1 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/18737364/
unhealthy, adult
Health Status: unhealthy
Age Group: adult
Sex: M
Sources:
https://pubmed.ncbi.nlm.nih.gov/18737364/
Other AEs: Spasms, Cyanosis...
Other AEs:
Spasms
Cyanosis
Respiration spontaneous decreased
Sources:
https://pubmed.ncbi.nlm.nih.gov/18737364/
10 % 1 times / day single, intraurethral
Studied dose
Dose: 10 %, 1 times / day
Route: intraurethral
Route: single
Dose: 10 %, 1 times / day
Sources:
https://jamanetwork.com/journals/jama/article-abstract/453290
healthy, adult
Health Status: healthy
Age Group: adult
Sex: M
Sources:
https://jamanetwork.com/journals/jama/article-abstract/453290
Other AEs: Generalised convulsion, Respiration spontaneous decreased...
Other AEs:
Generalised convulsion
Respiration spontaneous decreased
Cyanosis
Sources:
https://jamanetwork.com/journals/jama/article-abstract/453290
AEs

AEs

AESignificanceDosePopulation
Cyanosis
2 % 1 times / day single, intraurethral
Recommended
Dose: 2 %, 1 times / day
Route: intraurethral
Route: single
Dose: 2 %, 1 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/18737364/
unhealthy, adult
Health Status: unhealthy
Age Group: adult
Sex: M
Sources:
https://pubmed.ncbi.nlm.nih.gov/18737364/
Respiration spontaneous decreased
2 % 1 times / day single, intraurethral
Recommended
Dose: 2 %, 1 times / day
Route: intraurethral
Route: single
Dose: 2 %, 1 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/18737364/
unhealthy, adult
Health Status: unhealthy
Age Group: adult
Sex: M
Sources:
https://pubmed.ncbi.nlm.nih.gov/18737364/
Spasms
2 % 1 times / day single, intraurethral
Recommended
Dose: 2 %, 1 times / day
Route: intraurethral
Route: single
Dose: 2 %, 1 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/18737364/
unhealthy, adult
Health Status: unhealthy
Age Group: adult
Sex: M
Sources:
https://pubmed.ncbi.nlm.nih.gov/18737364/
Cyanosis
10 % 1 times / day single, intraurethral
Studied dose
Dose: 10 %, 1 times / day
Route: intraurethral
Route: single
Dose: 10 %, 1 times / day
Sources:
https://jamanetwork.com/journals/jama/article-abstract/453290
healthy, adult
Health Status: healthy
Age Group: adult
Sex: M
Sources:
https://jamanetwork.com/journals/jama/article-abstract/453290
Generalised convulsion
10 % 1 times / day single, intraurethral
Studied dose
Dose: 10 %, 1 times / day
Route: intraurethral
Route: single
Dose: 10 %, 1 times / day
Sources:
https://jamanetwork.com/journals/jama/article-abstract/453290
healthy, adult
Health Status: healthy
Age Group: adult
Sex: M
Sources:
https://jamanetwork.com/journals/jama/article-abstract/453290
Respiration spontaneous decreased
10 % 1 times / day single, intraurethral
Studied dose
Dose: 10 %, 1 times / day
Route: intraurethral
Route: single
Dose: 10 %, 1 times / day
Sources:
https://jamanetwork.com/journals/jama/article-abstract/453290
healthy, adult
Health Status: healthy
Age Group: adult
Sex: M
Sources:
https://jamanetwork.com/journals/jama/article-abstract/453290
Sourcing

Sourcing

Vendor/AggregatorIDURL
ABI Chem
AC1L1ZKO
Chemieliva Pharmaceutical Co., Ltd
PBCM1028265
ChemMol
99178506
http://www.chemmol.com/chemmol/99178506.html
ChemTik
CTK5H8665
eNovation Chemicals
K79446
https://www.enovationchem.com/ProductDetails.asp?ProductID=K79446
NovoSeek
12428
PubChem
12428
https://pubchem.ncbi.nlm.nih.gov/compound/12428
Smolecule
S518842
http://www.smolecule.com/products/s518842
THE BioTek
bt-259885
https://www.thebiotek.com/product/inhibitors/bt-259885
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:57:14 GMT 2025
Edited
by admin
on Mon Mar 31 18:57:14 GMT 2025
Record UNII
1801659K6K
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AMYDRICAINE
WHO-DD  
Common Name English
ALIPINA
Preferred Name English
2-BUTANOL, 1-(DIMETHYLAMINO)-2-((DIMETHYLAMINO)METHYL)-, BENZOATE
Systematic Name English
2-BENZOXY-2-DIMETHYLAMINOMETHYL-1-DIMETHYLAMINOBUTANE
Systematic Name English
ALYPIN
Brand Name English
1,1-BIS(DIMETHYLAMINOMETHYL)PROPYL BENZOATE
Systematic Name English
ALYPINE
Brand Name English
2-BUTANOL, 1-(DIMETHYLAMINO)-2-((DIMETHYLAMINO)METHYL)-, BENZOATE (ESTER)
Common Name English
Amydricaine [WHO-DD]
Common Name English
2-BUTANOL, 1-(DIMETHYLAMINO)-2-((DIMETHYLAMINO)METHYL)-, 2-BENZOATE
Common Name English
DIMETHYLAMINOSTOVAINE
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C245
Created by admin on Mon Mar 31 18:57:14 GMT 2025 , Edited by admin on Mon Mar 31 18:57:14 GMT 2025
Code System Code Type Description
ECHA (EC/EINECS)
213-512-6
Created by admin on Mon Mar 31 18:57:14 GMT 2025 , Edited by admin on Mon Mar 31 18:57:14 GMT 2025
PRIMARY
EPA CompTox
DTXSID70242192
Created by admin on Mon Mar 31 18:57:14 GMT 2025 , Edited by admin on Mon Mar 31 18:57:14 GMT 2025
PRIMARY
SMS_ID
100000077395
Created by admin on Mon Mar 31 18:57:14 GMT 2025 , Edited by admin on Mon Mar 31 18:57:14 GMT 2025
PRIMARY
EVMPD
SUB12889MIG
Created by admin on Mon Mar 31 18:57:14 GMT 2025 , Edited by admin on Mon Mar 31 18:57:14 GMT 2025
PRIMARY
CAS
963-07-5
Created by admin on Mon Mar 31 18:57:14 GMT 2025 , Edited by admin on Mon Mar 31 18:57:14 GMT 2025
PRIMARY
PUBCHEM
12428
Created by admin on Mon Mar 31 18:57:14 GMT 2025 , Edited by admin on Mon Mar 31 18:57:14 GMT 2025
PRIMARY
FDA UNII
1801659K6K
Created by admin on Mon Mar 31 18:57:14 GMT 2025 , Edited by admin on Mon Mar 31 18:57:14 GMT 2025
PRIMARY
NCI_THESAURUS
C96326
Created by admin on Mon Mar 31 18:57:14 GMT 2025 , Edited by admin on Mon Mar 31 18:57:14 GMT 2025
PRIMARY
NIH
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