Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C14H20N2O.ClH |
| Molecular Weight | 268.782 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CC(C)C1=CC=C(C)C=C1OCC2=NCCN2
InChI
InChIKey=DKIDQLUKAZZLAR-UHFFFAOYSA-N
InChI=1S/C14H20N2O.ClH/c1-10(2)12-5-4-11(3)8-13(12)17-9-14-15-6-7-16-14;/h4-5,8,10H,6-7,9H2,1-3H3,(H,15,16);1H
DescriptionSources: https://www.drugbank.ca/drugs/DB08803Curator's Comment: The description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/21796997 | https://www.ncbi.nlm.nih.gov/pubmed/2481638 | https://www.drugs.com/international/tymazoline.html
Sources: https://www.drugbank.ca/drugs/DB08803
Curator's Comment: The description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/21796997 | https://www.ncbi.nlm.nih.gov/pubmed/2481638 | https://www.drugs.com/international/tymazoline.html
Tymazoline (trade name Thymazen in Poland) is a nasal decongestant that can be used to treat rhinitis and nasal obstruction. Tymazoline is a drug with antihistaminic and sympathomimetic properties. It locally reduces swelling, inflammation and mucosal secretions of the nasal passages. Thymazen causes vasoconstriction of the nasal mucosa, reducing congestion and thus the swelling of the mucosa. Also reduces the secretions from the nose. Thymazen acts on alpha-adrenergic receptors, which reduces local inflammation of the nasal mucosa especially if their cause is an allergy.
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: CHEMBL231 Sources: Acta Poloniae Pharmaceutica (1960), 17, 349-53. |
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
Sources: https://www.drugbank.ca/drugs/DB08803 |
Primary | Thymazen Approved UseUnknown |
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06223H196A
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34153
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248-854-5
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28120-03-8
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SUB15641MIG
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100000077288
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ACTIVE MOIETY
SUBSTANCE RECORD