Details
Stereochemistry | ACHIRAL |
Molecular Formula | C14H20N2O |
Molecular Weight | 232.3214 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)C1=C(OCC2=NCCN2)C=C(C)C=C1
InChI
InChIKey=QRORCRWSRPKEHR-UHFFFAOYSA-N
InChI=1S/C14H20N2O/c1-10(2)12-5-4-11(3)8-13(12)17-9-14-15-6-7-16-14/h4-5,8,10H,6-7,9H2,1-3H3,(H,15,16)
Molecular Formula | C14H20N2O |
Molecular Weight | 232.3214 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
DescriptionSources: https://www.drugbank.ca/drugs/DB08803Curator's Comment: The description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/21796997 | https://www.ncbi.nlm.nih.gov/pubmed/2481638 | https://www.drugs.com/international/tymazoline.html
Sources: https://www.drugbank.ca/drugs/DB08803
Curator's Comment: The description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/21796997 | https://www.ncbi.nlm.nih.gov/pubmed/2481638 | https://www.drugs.com/international/tymazoline.html
Tymazoline (trade name Thymazen in Poland) is a nasal decongestant that can be used to treat rhinitis and nasal obstruction. Tymazoline is a drug with antihistaminic and sympathomimetic properties. It locally reduces swelling, inflammation and mucosal secretions of the nasal passages. Thymazen causes vasoconstriction of the nasal mucosa, reducing congestion and thus the swelling of the mucosa. Also reduces the secretions from the nose. Thymazen acts on alpha-adrenergic receptors, which reduces local inflammation of the nasal mucosa especially if their cause is an allergy.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL231 Sources: Acta Poloniae Pharmaceutica (1960), 17, 349-53. |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Sources: https://www.drugbank.ca/drugs/DB08803 |
Primary | Thymazen Approved UseUnknown |
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:30:49 GMT 2023
by
admin
on
Fri Dec 15 15:30:49 GMT 2023
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Record UNII |
U993RH5585
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Record Status |
Validated (UNII)
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Record Version |
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Common Name | English | ||
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Common Name | English |
Classification Tree | Code System | Code | ||
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WHO-VATC |
QR01AA13
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NCI_THESAURUS |
C29713
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WHO-ATC |
R01AA13
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DTXSID40178939
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24243-97-8
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100000077306
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Tymazoline
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U993RH5585
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m11285
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PRIMARY | Merck Index | ||
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DB08803
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SUB15640MIG
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CHEMBL2106467
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C95309
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3445
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34154
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Related Record | Type | Details | ||
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SALT/SOLVATE -> PARENT |