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Details

Stereochemistry ABSOLUTE
Molecular Formula C23H34O5
Molecular Weight 390.5131
Optical Activity UNSPECIFIED
Defined Stereocenters 8 / 8
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ALFADOLONE ACETATE

SMILES

CC(=O)OCC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3C(=O)C[C@]12C

InChI

InChIKey=QRJOQYLXZPQQMX-FWROMSNXSA-N
InChI=1S/C23H34O5/c1-13(24)28-12-20(27)18-7-6-17-16-5-4-14-10-15(25)8-9-22(14,2)21(16)19(26)11-23(17,18)3/h14-18,21,25H,4-12H2,1-3H3/t14-,15+,16-,17-,18+,21+,22-,23-/m0/s1

HIDE SMILES / InChI

Description

Alfadolone or alphadolone is an oral neurosteroid, which can be useful as an analgesic.

Approval Year

Unknown
149124
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Not Provided
511
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed

Sample Use Guides

In Vivo Use Guide
alphadolone (25-500 mg, n = 9) or placebo (lactose, n = 5) given orally 1 h after operation
Route of Administration: Oral
In Vitro Use Guide
Unknown
Name Type Language
ALFADOLONE ACETATE [MI]
Preferred Name English
ALFADOLONE ACETATE
MART.   MI   WHO-DD  
Common Name English
Alfadolone acetate [WHO-DD]
Common Name English
ALFADOLONE ACETATE [MART.]
Common Name English
ALPHADOLONE ACETATE
Common Name English
PREGNANE-11,20-DIONE, 21-(ACETYLOXY)-3-HYDROXY-, (3.ALPHA.,5.ALPHA.)-
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C241
Created by admin on Mon Mar 31 18:38:46 GMT 2025 , Edited by admin on Mon Mar 31 18:38:46 GMT 2025
Code System Code Type Description
ECHA (EC/EINECS)
245-942-5
Created by admin on Mon Mar 31 18:38:46 GMT 2025 , Edited by admin on Mon Mar 31 18:38:46 GMT 2025
PRIMARY
NCI_THESAURUS
C98249
Created by admin on Mon Mar 31 18:38:46 GMT 2025 , Edited by admin on Mon Mar 31 18:38:46 GMT 2025
PRIMARY
MESH
C033418
Created by admin on Mon Mar 31 18:38:46 GMT 2025 , Edited by admin on Mon Mar 31 18:38:46 GMT 2025
PRIMARY
MERCK INDEX
m1498
Created by admin on Mon Mar 31 18:38:46 GMT 2025 , Edited by admin on Mon Mar 31 18:38:46 GMT 2025
PRIMARY Merck Index
CAS
23930-37-2
Created by admin on Mon Mar 31 18:38:46 GMT 2025 , Edited by admin on Mon Mar 31 18:38:46 GMT 2025
PRIMARY
EVMPD
SUB00336MIG
Created by admin on Mon Mar 31 18:38:46 GMT 2025 , Edited by admin on Mon Mar 31 18:38:46 GMT 2025
PRIMARY
DRUG CENTRAL
5045
Created by admin on Mon Mar 31 18:38:46 GMT 2025 , Edited by admin on Mon Mar 31 18:38:46 GMT 2025
PRIMARY
WIKIPEDIA
Alfadolone acetate
Created by admin on Mon Mar 31 18:38:46 GMT 2025 , Edited by admin on Mon Mar 31 18:38:46 GMT 2025
PRIMARY
SMS_ID
100000078856
Created by admin on Mon Mar 31 18:38:46 GMT 2025 , Edited by admin on Mon Mar 31 18:38:46 GMT 2025
PRIMARY
EPA CompTox
DTXSID7045443
Created by admin on Mon Mar 31 18:38:46 GMT 2025 , Edited by admin on Mon Mar 31 18:38:46 GMT 2025
PRIMARY
FDA UNII
00TN4GS00S
Created by admin on Mon Mar 31 18:38:46 GMT 2025 , Edited by admin on Mon Mar 31 18:38:46 GMT 2025
PRIMARY
PUBCHEM
24733
Created by admin on Mon Mar 31 18:38:46 GMT 2025 , Edited by admin on Mon Mar 31 18:38:46 GMT 2025
PRIMARY
ACTIVE MOIETY
Structure of ALFADOLONE
SUBSTANCE RECORD
Structure of ALFADOLONE ACETATE
NIH
NCATS
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