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Search results for "empagliflozin" in Related Substance Name (exact match)

Showing 1 - 10 of 13 results

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EMPAGLIFLOZIN

HDC1R2M35U

Search for Structure

Status:

US Approved Rx (2020)

Source:

NDA212614

(2020)

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=212614

First approved in 2014

Source:

NDA204629

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=204629

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Sodium/glucose cotransporter 2

Conditions:

Type 2 diabetes mellitus

Empagliflozin is a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor designed for the treatment of type 2 diabetes mellitus. By inhibiting SGLT2, empagliflozin reduces renal reabsorption of filtered glucose and lowers the renal threshold for glucose, and thereby increases urinary glucose excretion. Empagliflozin interacts with diuretics, blood presure medicine and insulin. Jardiance reduces the risk of cardiovascular death in diabetes patients at high cardiovascular risk.

(2S,3R,4R,5S,6R)-2-(4-CHLORO-3-((4-((1S)-3-HYDROXY-1-(HYDROXYMETHYL)PROPOXY)PHENYL)METHYL)PHENYL)-6-(HYDROXYMETHYL)TETRAHYDROPYRAN-3,4,5-TRIOL

VPF7YG4E9B

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

3'-EPI EMPAGLIFLOZIN

RU69F6Q4ZE

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

(S)-3-(4-(2-CHLOROBENZYL)PHENOXY)TETRAHYDROFURAN

7CY9RZ5RX9

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

(S)-3-(4-(5-BROMO-2-CHLOROBENZYL)PHENOXY)TETRAHYDROFURAN

4WR8P4HZ8G

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

(2S,3S,4S,5R,6R)-6-(((2R,3S,4R,5R,6S)-6-(4-CHLORO-3-((4-((3S)-TETRAHYDROFURAN-3-YL)OXYPHENYL)METHYL)PHENYL)-3,4,5-TRIHYDROXY-TETRAHYDROPYRAN-2-YL)METHOXY)-3,4,5-TRIHYDROXY-TETRAHYDROPYRAN-2-CARBOXYLIC ACID

GAJ6QB3GML

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

(2S,3S,4S,5R)-6-((2S,3S,4R,5R,6R)-2-(4-CHLORO-3-((4-((3S)-TETRAHYDROFURAN-3-YL)OXYPHENYL)METHYL)PHENYL)-3,5-DIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDROPYRAN-4-YL)OXY-3,4,5-TRIHYDROXY-TETRAHYDROPYRAN-2-CARBOXYLIC ACID

2Y9V2N2EPY

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

(2S,3S,4S,5R,6R)-6-((2S,3R,4S,5S,6R)-2-(4-CHLORO-3-((4-((3S)-TETRAHYDROFURAN-3-YL)OXYPHENYL)METHYL)PHENYL)-4,5-DIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDROPYRAN-3-YL)OXY-3,4,5-TRIHYDROXY-TETRAHYDROPYRAN-2-CARBOXYLIC ACID

QG8UC6R6QD

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

PLASMA PROTEIN FRACTION (HUMAN)

6D53G0FD0Z

Status:

Possibly Marketed Outside US

Source:

Octaplasma by Octapharma Pharmazeutika Produktionsges M B H [Canada]

Source URL:

https://www.drugbank.ca/drugs/DB13968

First approved in 2013

Source:

BLA125416

Source URL:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=998415d8-9bbe-e5b8-c3b0-3ba0344faacb

Class:

MIXTURE

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A8

S5EY2C8G0B

Subunit 1 (505) Similarity Search

Sequence Search

Subunit 1 (505) Similarity Search

Status:

Other

Class:

PROTEIN

Structure of EMPAGLIFLOZIN

ABSOLUTE

Structure of (2S,3R,4R,5S,6R)-2-(4-CHLORO-3-((4-((1S)-3-HYDROXY-1-(HYDROXYMETHYL)PROPOXY)PHENYL)METHYL)PHENYL)-6-(HYDROXYMETHYL)TETRAHYDROPYRAN-3,4,5-TRIOL

ABSOLUTE

(2S,3R,4R,5S,6R)-2-(4-CHLORO-3-((4-((1S)-3-HYDROXY-1-(HYDROXYMETHYL)PROPOXY)PHENYL)METHYL)PHENYL)-6-(HYDROXYMETHYL)TETRAHYDROPYRAN-3,4,5-TRIOL

Structure of 3'-EPI EMPAGLIFLOZIN

ABSOLUTE

3'-EPI EMPAGLIFLOZIN

Structure of (S)-3-(4-(2-CHLOROBENZYL)PHENOXY)TETRAHYDROFURAN

ABSOLUTE

(S)-3-(4-(2-CHLOROBENZYL)PHENOXY)TETRAHYDROFURAN

Structure of (S)-3-(4-(5-BROMO-2-CHLOROBENZYL)PHENOXY)TETRAHYDROFURAN

ABSOLUTE

(S)-3-(4-(5-BROMO-2-CHLOROBENZYL)PHENOXY)TETRAHYDROFURAN

Structure of (2S,3S,4S,5R,6R)-6-(((2R,3S,4R,5R,6S)-6-(4-CHLORO-3-((4-((3S)-TETRAHYDROFURAN-3-YL)OXYPHENYL)METHYL)PHENYL)-3,4,5-TRIHYDROXY-TETRAHYDROPYRAN-2-YL)METHOXY)-3,4,5-TRIHYDROXY-TETRAHYDROPYRAN-2-CARBOXYLIC ACID

ABSOLUTE

(2S,3S,4S,5R,6R)-6-(((2R,3S,4R,5R,6S)-6-(4-CHLORO-3-((4-((3S)-TETRAHYDROFURAN-3-YL)OXYPHENYL)METHYL)PHENYL)-3,4,5-TRIHYDROXY-TETRAHYDROPYRAN-2-YL)METHOXY)-3,4,5-TRIHYDROXY-TETRAHYDROPYRAN-2-CARBOXYLIC ACID

Structure of (2S,3S,4S,5R)-6-((2S,3S,4R,5R,6R)-2-(4-CHLORO-3-((4-((3S)-TETRAHYDROFURAN-3-YL)OXYPHENYL)METHYL)PHENYL)-3,5-DIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDROPYRAN-4-YL)OXY-3,4,5-TRIHYDROXY-TETRAHYDROPYRAN-2-CARBOXYLIC ACID

ABSOLUTE

(2S,3S,4S,5R)-6-((2S,3S,4R,5R,6R)-2-(4-CHLORO-3-((4-((3S)-TETRAHYDROFURAN-3-YL)OXYPHENYL)METHYL)PHENYL)-3,5-DIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDROPYRAN-4-YL)OXY-3,4,5-TRIHYDROXY-TETRAHYDROPYRAN-2-CARBOXYLIC ACID

Structure of (2S,3S,4S,5R,6R)-6-((2S,3R,4S,5S,6R)-2-(4-CHLORO-3-((4-((3S)-TETRAHYDROFURAN-3-YL)OXYPHENYL)METHYL)PHENYL)-4,5-DIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDROPYRAN-3-YL)OXY-3,4,5-TRIHYDROXY-TETRAHYDROPYRAN-2-CARBOXYLIC ACID

ABSOLUTE

(2S,3S,4S,5R,6R)-6-((2S,3R,4S,5S,6R)-2-(4-CHLORO-3-((4-((3S)-TETRAHYDROFURAN-3-YL)OXYPHENYL)METHYL)PHENYL)-4,5-DIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDROPYRAN-3-YL)OXY-3,4,5-TRIHYDROXY-TETRAHYDROPYRAN-2-CARBOXYLIC ACID

Mixture

PLASMA PROTEIN FRACTION (HUMAN)

Protein

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A8

Showing 1 - 10 of 13 results

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HHS VULNERABILITY DISCLOSURE

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