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Search results for "daclatasvir" in Related Substance Name (exact match)

Showing 1 - 10 of 12 results

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METHYL N-((1S)-2-METHYL-1-((2S)-2-(5-(4-(4-OXALDEHYDOYLPHENYL)PHENYL)-1H-IMIDAZOL-2-YL)PYRROLIDINE-1-CARBONYL)PROPYL)CARBAMATE

GE6B44J7GP

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

CARBAMIC ACID, N-((1S)-1-(((2S)-2-(5-(4'-(2-((2R,3R)-3-HYDROXY-1-((2S)-2-((METHOXYCARBONYL)AMINO)-3-METHYL-1-OXOBUTYL)-2-PYRROLIDINYL)-1H-IMIDAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)-1H-IMIDAZOL-2-YL)-1-PYRROLIDINYL)CARBONYL)-2-METHYLPROPYL)-, METHYL ESTER

P7BC3Z5VM7

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

METHYL N-((1S)-1-((2S)-2-(5-(4-(4-((8S)-8-(((2S)-2-AMINO-3-METHYL-BUTANOYL)AMINO)-5-HYDROXY-5,6,7,8-TETRAHYDROIMIDAZO(1,2-A)PYRIDIN-3-YL)PHENYL)PHENYL)-1H-IMIDAZOL-2-YL)PYRROLIDINE-1-CARBONYL)-2-METHYL-PROPYL)CARBAMATE

H8C9RV6JWH

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (EPIMERIC)

CARBAMIC ACID, N-((1S)-1-(((2S)-2-(5-(4'-(2-((2S)-1-((2S)-2-AMINO-3-METHYL-1-OXOBUTYL)-2-PYRROLIDINYL)-1H-IMIDAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)-1H-IMIDAZOL-2-YL)-1-PYRROLIDINYL)CARBONYL)-2-METHYLPROPYL)-, METHYL ESTER

5V6X9P8JH9

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

4'-(2-((2S)-1-((2S)-2-((METHOXYCARBONYL)AMINO)-3-METHYL-1-OXOBUTYL)-2-PYRROLIDINYL)-1H-IMIDAZOL-5-YL)(1,1'-BIPHENYL)-4-CARBOXYLIC ACID

4K8JA2N2S8

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

CARBAMIC ACID, N-((1S)-1-(((2S)-2-(5-(4'-(2-((2S)-1-((2S,3R)-4-HYDROXY-2-((METHOXYCARBONYL)AMINO)-3-METHYL-1-OXOBUTYL)-2-PYRROLIDINYL)-1H-IMIDAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)-1H-IMIDAZOL-2-YL)-1-PYRROLIDINYL)CARBONYL)-2-METHYLPROPYL)-, METHYL ESTER

SY6HPB2YFS

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

2-(4-(4-(2-((2S)-1-((2S)-2-(METHOXYCARBONYLAMINO)-3-METHYL-BUTANOYL)PYRROLIDIN-2-YL)-1H-IMIDAZOL-5-YL)PHENYL)PHENYL)-2-OXO-ACETIC ACID

3BP5HX5KJU

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

DACLATASVIR

LI2427F9CI

Search for Structure

Status:

US Previously Marketed

Source:

DAKLINZA by BRISTOL-MYERS SQUIBB

(2015)

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=206843

First approved in 2015

Source:

DAKLINZA by BRISTOL-MYERS SQUIBB

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=206843

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Nonstructural protein 5A

Conditions:

Chronic hepatitis C virus genotype 3 infection

Daclatasvir (BMS-790052) is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 3 infection. Daclatasvir prevents RNA replication and virion assembly by binding to NS5A, a nonstructural phosphoprotein encoded by HCV. Binding to the N-terminus of the D1 domain of NS5A prevents its interaction with host cell proteins and membranes required for virion replication complex assembly.

PLASMA PROTEIN FRACTION (HUMAN)

6D53G0FD0Z

Status:

Possibly Marketed Outside US

Source:

Octaplasma by Octapharma Pharmazeutika Produktionsges M B H [Canada]

Source URL:

https://www.drugbank.ca/drugs/DB13968

First approved in 2013

Source:

BLA125416

Source URL:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=998415d8-9bbe-e5b8-c3b0-3ba0344faacb

Class:

MIXTURE

MULTIDRUG RESISTANCE PROTEIN 1

22ES734693

Subunit 1 (1280) Similarity Search

Sequence Search

Subunit 1 (1280) Similarity Search

Status:

Other

Class:

PROTEIN

Structure of METHYL N-((1S)-2-METHYL-1-((2S)-2-(5-(4-(4-OXALDEHYDOYLPHENYL)PHENYL)-1H-IMIDAZOL-2-YL)PYRROLIDINE-1-CARBONYL)PROPYL)CARBAMATE

ABSOLUTE

METHYL N-((1S)-2-METHYL-1-((2S)-2-(5-(4-(4-OXALDEHYDOYLPHENYL)PHENYL)-1H-IMIDAZOL-2-YL)PYRROLIDINE-1-CARBONYL)PROPYL)CARBAMATE

Structure of CARBAMIC ACID, N-((1S)-1-(((2S)-2-(5-(4'-(2-((2R,3R)-3-HYDROXY-1-((2S)-2-((METHOXYCARBONYL)AMINO)-3-METHYL-1-OXOBUTYL)-2-PYRROLIDINYL)-1H-IMIDAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)-1H-IMIDAZOL-2-YL)-1-PYRROLIDINYL)CARBONYL)-2-METHYLPROPYL)-, METHYL ESTER

ABSOLUTE

CARBAMIC ACID, N-((1S)-1-(((2S)-2-(5-(4'-(2-((2R,3R)-3-HYDROXY-1-((2S)-2-((METHOXYCARBONYL)AMINO)-3-METHYL-1-OXOBUTYL)-2-PYRROLIDINYL)-1H-IMIDAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)-1H-IMIDAZOL-2-YL)-1-PYRROLIDINYL)CARBONYL)-2-METHYLPROPYL)-, METHYL ESTER

Structure of METHYL N-((1S)-1-((2S)-2-(5-(4-(4-((8S)-8-(((2S)-2-AMINO-3-METHYL-BUTANOYL)AMINO)-5-HYDROXY-5,6,7,8-TETRAHYDROIMIDAZO(1,2-A)PYRIDIN-3-YL)PHENYL)PHENYL)-1H-IMIDAZOL-2-YL)PYRROLIDINE-1-CARBONYL)-2-METHYL-PROPYL)CARBAMATE

EPIMERIC

METHYL N-((1S)-1-((2S)-2-(5-(4-(4-((8S)-8-(((2S)-2-AMINO-3-METHYL-BUTANOYL)AMINO)-5-HYDROXY-5,6,7,8-TETRAHYDROIMIDAZO(1,2-A)PYRIDIN-3-YL)PHENYL)PHENYL)-1H-IMIDAZOL-2-YL)PYRROLIDINE-1-CARBONYL)-2-METHYL-PROPYL)CARBAMATE

Structure of CARBAMIC ACID, N-((1S)-1-(((2S)-2-(5-(4'-(2-((2S)-1-((2S)-2-AMINO-3-METHYL-1-OXOBUTYL)-2-PYRROLIDINYL)-1H-IMIDAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)-1H-IMIDAZOL-2-YL)-1-PYRROLIDINYL)CARBONYL)-2-METHYLPROPYL)-, METHYL ESTER

ABSOLUTE

CARBAMIC ACID, N-((1S)-1-(((2S)-2-(5-(4'-(2-((2S)-1-((2S)-2-AMINO-3-METHYL-1-OXOBUTYL)-2-PYRROLIDINYL)-1H-IMIDAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)-1H-IMIDAZOL-2-YL)-1-PYRROLIDINYL)CARBONYL)-2-METHYLPROPYL)-, METHYL ESTER

Structure of 4'-(2-((2S)-1-((2S)-2-((METHOXYCARBONYL)AMINO)-3-METHYL-1-OXOBUTYL)-2-PYRROLIDINYL)-1H-IMIDAZOL-5-YL)(1,1'-BIPHENYL)-4-CARBOXYLIC ACID

ABSOLUTE

4'-(2-((2S)-1-((2S)-2-((METHOXYCARBONYL)AMINO)-3-METHYL-1-OXOBUTYL)-2-PYRROLIDINYL)-1H-IMIDAZOL-5-YL)(1,1'-BIPHENYL)-4-CARBOXYLIC ACID

Structure of CARBAMIC ACID, N-((1S)-1-(((2S)-2-(5-(4'-(2-((2S)-1-((2S,3R)-4-HYDROXY-2-((METHOXYCARBONYL)AMINO)-3-METHYL-1-OXOBUTYL)-2-PYRROLIDINYL)-1H-IMIDAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)-1H-IMIDAZOL-2-YL)-1-PYRROLIDINYL)CARBONYL)-2-METHYLPROPYL)-, METHYL ESTER

ABSOLUTE

CARBAMIC ACID, N-((1S)-1-(((2S)-2-(5-(4'-(2-((2S)-1-((2S,3R)-4-HYDROXY-2-((METHOXYCARBONYL)AMINO)-3-METHYL-1-OXOBUTYL)-2-PYRROLIDINYL)-1H-IMIDAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)-1H-IMIDAZOL-2-YL)-1-PYRROLIDINYL)CARBONYL)-2-METHYLPROPYL)-, METHYL ESTER

Structure of 2-(4-(4-(2-((2S)-1-((2S)-2-(METHOXYCARBONYLAMINO)-3-METHYL-BUTANOYL)PYRROLIDIN-2-YL)-1H-IMIDAZOL-5-YL)PHENYL)PHENYL)-2-OXO-ACETIC ACID

ABSOLUTE

2-(4-(4-(2-((2S)-1-((2S)-2-(METHOXYCARBONYLAMINO)-3-METHYL-BUTANOYL)PYRROLIDIN-2-YL)-1H-IMIDAZOL-5-YL)PHENYL)PHENYL)-2-OXO-ACETIC ACID

Structure of DACLATASVIR

ABSOLUTE

Mixture

PLASMA PROTEIN FRACTION (HUMAN)

Protein

MULTIDRUG RESISTANCE PROTEIN 1

Showing 1 - 10 of 12 results

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