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Search results for methadone in Any Name (approximate match)
Status:
US Approved Rx
(2015)
Source:
ANDA203502
(2015)
Source URL:
First approved in 1947
Source:
NDA021624
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Methadone, sold under the brand names Dolophine among others, is an synthetic opioid that is used as the hydrochloride to treat pain and as maintenance therapy or to help with detoxification in people with opioid dependence. Methadone hydrochloride is a mu-agonist; a synthetic opioid analgesic with multiple actions qualitatively similar to those of morphine. Some data also indicate that methadone acts as an antagonist at the NMDA-receptor. The contribution of NMDA receptor antagonism to methadone’s efficacy is unknown. Most common adverse reactions are: lightheadedness, dizziness, sedation, nausea, vomiting, and sweating. Avoid use mixed agonist/antagonist and partial agonist opioid analgesics with DOLOPHINE because they may reduce analgesic effect of DOLOPHINE or precipitate withdrawal symptoms.
Status:
Investigational
Source:
INN:isomethadone [INN]
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
ISOMETHADONE HYDROBROMIDE, DL- is a hydrobromide salt of isomethadone, a synthetic opioid analgesic. This is a controlled substance in the US.
Status:
Investigational
Source:
INN:esmethadone [INN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Didiavalo (premethadone) is a methadone analog and precursor. Didiavalo possesses analgetic properties with the effective dose in rats 30 times higher than the analgesic dose of morphine.
Status:
Possibly Marketed Outside US
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
levomethadone, or R-(−)-methadone, is the active enantiomer of methadone; having approximately 50x the potency of the S-(+)-enantiomer as well as greater μ-opioid receptor selectivity.
Status:
US Approved Rx
(2015)
Source:
ANDA203502
(2015)
Source URL:
First approved in 1947
Source:
NDA021624
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Methadone, sold under the brand names Dolophine among others, is an synthetic opioid that is used as the hydrochloride to treat pain and as maintenance therapy or to help with detoxification in people with opioid dependence. Methadone hydrochloride is a mu-agonist; a synthetic opioid analgesic with multiple actions qualitatively similar to those of morphine. Some data also indicate that methadone acts as an antagonist at the NMDA-receptor. The contribution of NMDA receptor antagonism to methadone’s efficacy is unknown. Most common adverse reactions are: lightheadedness, dizziness, sedation, nausea, vomiting, and sweating. Avoid use mixed agonist/antagonist and partial agonist opioid analgesics with DOLOPHINE because they may reduce analgesic effect of DOLOPHINE or precipitate withdrawal symptoms.