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Search results for flumazenil in Display Name (approximate match)
Showing 1 - 6 of 6 results
Status:
US Approved Rx
(2004)
Source:
ANDA076787
(2004)
Source URL:
First approved in 1991
Source:
ROMAZICON by HOFFMANN LA ROCHE
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system. Fumazenil is used for the complete or partial reversal of the sedative effects of benzodiazepines in cases where general anesthesia has been induced and/or maintained with benzodiazepines, and where sedation has been produced with benzodiazepines for diagnostic and therapeutic procedures. Also for the management of benzodiazepine overdose as an adjunct for appropriate supportive and symptomatic measures. Flumazenil went off patent in 2008 so at present generic formulations of this drug are available.
Status:
Investigational
Source:
NCT04308954: Phase 1 Interventional Terminated Fragile X Syndrome (FXS)
(2016)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Investigational
Source:
NCT01904487: Phase 1 Interventional Completed Alcoholism
(2011)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
