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Restrict the search for
doravirine
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There is one exact (name or code) match for doravirine
Status:
US Approved Rx
(2018)
Source:
NDA210807
(2018)
Source URL:
First approved in 2018
Source:
NDA210806
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Doravirine (MK-1439) is a nonnucleoside inhibitor of HIV reverse transcriptase (NNRTI). It displays excellent activities against not only WT viruses but also a broader panel of NNRTI-resistant viruses. Doravirine is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults who have never taken HIV medicines before. Doravirine is always used in combination with other HIV medicines.
Status:
US Approved Rx
(2018)
Source:
NDA210807
(2018)
Source URL:
First approved in 2018
Source:
NDA210806
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Doravirine (MK-1439) is a nonnucleoside inhibitor of HIV reverse transcriptase (NNRTI). It displays excellent activities against not only WT viruses but also a broader panel of NNRTI-resistant viruses. Doravirine is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults who have never taken HIV medicines before. Doravirine is always used in combination with other HIV medicines.
Status:
US Approved Rx
(1995)
Source:
NDA020564
(1995)
Source URL:
First approved in 1995
Source:
NDA020564
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Lamivudine is a reverse transcriptase inhibitor used alone or in combination with other classes of anti-human immunodeficiency virus (HIV) drugs in the treatment of HIV infection. This molecule has two stereo-centers, thus giving rise to four stereoisomers: (+/-)-cis-lamivudine and (+/-)-trans-lamivudine. The latter is considered to be impurity of the pharmaceutically active isomer, (-)-cis-lamivudine.
![Structure of 3-[3-Chloro-5-[4-(trifluoromethyl)-2-pyrimidinyl]phenoxy]-1-[(4,5-dihydro-4-methyl-5-oxo-1H-1,2,4-triazol-3-yl)methyl]-4-(trifluoromethyl)-2(1H)-pyridinone](/img/302d12ba-9c99-4785-b533-b6daa2db8fc7.svg?size=200&context=ogkhpuvsze)
![Structure of 3-Chloro-5-[[1-[[1-[(4,5-dihydro-4-methyl-5-oxo-1H-1,2,4-triazol-3-yl)methyl]-4,5-dihydro-4-methyl-5-oxo-1H-1,2,4-triazol-3-yl]methyl]-1,2-dihydro-2-oxo-4-(trifluoromethyl)-3-pyridinyl]oxy]benzonitrile](/img/0c145595-7d90-48fc-a0da-ca550e0656cc.svg?size=200&context=ogkhpuvsze)
![Structure of 3-Chloro-5-[[1-[(4,5-dihydro-4-methyl-5-oxo-1H-1,2,4-triazol-3-yl)methyl]-1,2-dihydro-2-oxo-4-(trifluoromethyl)-3-pyridinyl]oxy]benzenecarbothioamide](/img/5bbd20ee-92fb-424e-8067-34207b0fddef.svg?size=200&context=ogkhpuvsze)
![Structure of 3-Chloro-5-[[1,2-dihydro-1-methyl-2-oxo-4-(trifluoromethyl)-3-pyridinyl]oxy]benzonitrile](/img/52f9ef44-0aac-4b22-bbc6-ba3c4df439c6.svg?size=200&context=ogkhpuvsze)
