U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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There is one exact (name or code) match for diphenylpyraline

 
Status:
US Previously Marketed
Source:
PYRALINE HCL 2MG by NOPCO
(1961)
Source URL:
First approved in 1953
Source:
Diafen by SchenLabs (Riker)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Diphenylpyraline is an antihistamine that prevents but does not reverse, responses mediated by histamine alone. Diphenylpyraline antagonizes most of the pharmacological effects of histamine, including urticaria and pruritus. Also, diphenylpyraline may exhibit anticholinergic actions (as do most of the antihistamines) and may thus provide a drying effect on the nasal mucosa. Antihistamines such as diphenylpyraline used in the treatment of allergy act by competing with histamine for H1-receptor sites on effector cells. This reduces the effects of histamine, leading to a temporary reduction of allergy symptoms.
Status:
US Previously Marketed
Source:
PYRALINE HCL 2MG by NOPCO
(1961)
Source URL:
First approved in 1953
Source:
Diafen by SchenLabs (Riker)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Diphenylpyraline is an antihistamine that prevents but does not reverse, responses mediated by histamine alone. Diphenylpyraline antagonizes most of the pharmacological effects of histamine, including urticaria and pruritus. Also, diphenylpyraline may exhibit anticholinergic actions (as do most of the antihistamines) and may thus provide a drying effect on the nasal mucosa. Antihistamines such as diphenylpyraline used in the treatment of allergy act by competing with histamine for H1-receptor sites on effector cells. This reduces the effects of histamine, leading to a temporary reduction of allergy symptoms.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Piprinhydrinate is compositon of Diphenylpyraline and 8-chloroteophylline. 8-Chlorotheophylline is a stimulant drug of the xanthine chemical class, with physiological effects similar to caffeine. Diphenylpyraline is an antihistamine that prevents, but does not reverse, responses mediated by histamine alone. Diphenylpyraline antagonizes most of the pharmacological effects of histamine, including urticaria and pruritus. Also, diphenylpyraline may exhibit anticholinergic actions (as do most of the antihistamines) and may thus provide a drying effect on the nasal mucosa. 8-Chlorotheophylline main use is in combination with Diphenylpyraline or diphenhydramine in the antiemetic Piprinhydrinate and dimenhydrinate. Diphenylpyraline (or diphenhydramine) reduces nausea but causes drowsiness, and the stimulant properties of 8-Chlorotheophylline help ward off that side-effect.
Status:
US Previously Marketed
Source:
PYRALINE HCL 2MG by NOPCO
(1961)
Source URL:
First approved in 1953
Source:
Diafen by SchenLabs (Riker)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Diphenylpyraline is an antihistamine that prevents but does not reverse, responses mediated by histamine alone. Diphenylpyraline antagonizes most of the pharmacological effects of histamine, including urticaria and pruritus. Also, diphenylpyraline may exhibit anticholinergic actions (as do most of the antihistamines) and may thus provide a drying effect on the nasal mucosa. Antihistamines such as diphenylpyraline used in the treatment of allergy act by competing with histamine for H1-receptor sites on effector cells. This reduces the effects of histamine, leading to a temporary reduction of allergy symptoms.
Status:
US Previously Marketed
Source:
PYRALINE HCL 2MG by NOPCO
(1961)
Source URL:
First approved in 1953
Source:
Diafen by SchenLabs (Riker)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Diphenylpyraline is an antihistamine that prevents but does not reverse, responses mediated by histamine alone. Diphenylpyraline antagonizes most of the pharmacological effects of histamine, including urticaria and pruritus. Also, diphenylpyraline may exhibit anticholinergic actions (as do most of the antihistamines) and may thus provide a drying effect on the nasal mucosa. Antihistamines such as diphenylpyraline used in the treatment of allergy act by competing with histamine for H1-receptor sites on effector cells. This reduces the effects of histamine, leading to a temporary reduction of allergy symptoms.