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Restrict the search for decitabine to a specific field?

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root_modifications_agentModifications_agentSubstance_refPname

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There is one exact (name or code) match for decitabine

DECITABINE

776B62CQ27

Search for Structure

Status:

US Approved Rx (2013)

Source:

ANDA203131

(2013)

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=203131

First approved in 2006

Source:

DACOGEN by OTSUKA

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=021790

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

DNA (cytosine-5)-methyltransferase 1

Conditions:

Myelodysplastic syndromes

Decitabine was first synthesized by Pliml and Sorm in the Institute of Organic Chemistry, Czechoslovak Academy of Sciences in 1964. Later, the drug was approved by FDA for the treatment of myelodysplastic syndromes in patients with cancer. Upon administration the decitabine is metabolized to the active phosphorylated metabolite which is incorporated into DNA and thus inhibits DNA methyltransferase (decitabine deplete DNMT1).

Showing 1 - 10 of 22 results

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DECITABINE

776B62CQ27

Search for Structure

Status:

US Approved Rx (2013)

Source:

ANDA203131

(2013)

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=203131

First approved in 2006

Source:

DACOGEN by OTSUKA

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=021790

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

DNA (cytosine-5)-methyltransferase 1

Conditions:

Myelodysplastic syndromes

Decitabine was first synthesized by Pliml and Sorm in the Institute of Organic Chemistry, Czechoslovak Academy of Sciences in 1964. Later, the drug was approved by FDA for the treatment of myelodysplastic syndromes in patients with cancer. Upon administration the decitabine is metabolized to the active phosphorylated metabolite which is incorporated into DNA and thus inhibits DNA methyltransferase (decitabine deplete DNMT1).

Methyl 2-deoxy-3,5-di-O-p-toluoyl-α-D-ribofuranoside

AW9MZ2SQL5

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

α-D-erythro-Pentopyranoside, methyl 2-deoxy-, bis(4-methylbenzoate)

DHK26M66ZJ

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

2-Deoxy-D-erythro-pentopyranosyl chloride bis(4-methylbenzoate)

9HJE9RU7ZN

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one

QA87CSB8QS

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

Methyl 2-deoxy-3,5-di-O-p-toluoyl-β-D-ribofuranoside

QL42HJQ8DS

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

2-Deoxy-5-O-(4-phenylbenzoyl)-D-erythro-pentofuranose

7DTZ95Q75S

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (EPIMERIC)

1-(2-DEOXY-5-O-PHOSPHONO-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-1,3,5-TRIAZINE-2,4(1H,3H)-DIONE

T6XKB2ZT5Q

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

5-AZA-2'-DEOXYCYTIDINE 5'-MONOPHOSPHATE

Y8E227WD26

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

5-AZA-2'-DEOXYCYTIDINE TRIPHOSPHATE

DJX4AL4ENX

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

Structure of DECITABINE

ABSOLUTE

Structure of Methyl 2-deoxy-3,5-di-O-p-toluoyl-α-D-ribofuranoside

ABSOLUTE

Methyl 2-deoxy-3,5-di-O-p-toluoyl-α-D-ribofuranoside

Structure of α-D-erythro-Pentopyranoside, methyl 2-deoxy-, bis(4-methylbenzoate)

ABSOLUTE

α-D-erythro-Pentopyranoside, methyl 2-deoxy-, bis(4-methylbenzoate)

Structure of 2-Deoxy-D-erythro-pentopyranosyl chloride bis(4-methylbenzoate)

ABSOLUTE

2-Deoxy-D-erythro-pentopyranosyl chloride bis(4-methylbenzoate)

Structure of 4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one

ABSOLUTE

4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one

Structure of Methyl 2-deoxy-3,5-di-O-p-toluoyl-β-D-ribofuranoside

ABSOLUTE

Methyl 2-deoxy-3,5-di-O-p-toluoyl-β-D-ribofuranoside

Structure of 2-Deoxy-5-O-(4-phenylbenzoyl)-D-erythro-pentofuranose

EPIMERIC

2-Deoxy-5-O-(4-phenylbenzoyl)-D-erythro-pentofuranose

Structure of 1-(2-DEOXY-5-O-PHOSPHONO-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-1,3,5-TRIAZINE-2,4(1H,3H)-DIONE

ABSOLUTE

1-(2-DEOXY-5-O-PHOSPHONO-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-1,3,5-TRIAZINE-2,4(1H,3H)-DIONE

Structure of 5-AZA-2'-DEOXYCYTIDINE 5'-MONOPHOSPHATE

ABSOLUTE

5-AZA-2'-DEOXYCYTIDINE 5'-MONOPHOSPHATE

Structure of 5-AZA-2'-DEOXYCYTIDINE TRIPHOSPHATE

ABSOLUTE

5-AZA-2'-DEOXYCYTIDINE TRIPHOSPHATE

Showing 1 - 10 of 22 results

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