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Showing 1 - 6 of 6 results

Status:
US Approved Rx (2020)
First approved in 2009

Class (Stereo):
CHEMICAL (RACEMIC)



Asenapine is an antipsychotic drug. The mechanism of action of asenapine, as with other drugs having efficacy in schizophrenia and bipolar disorder, is unknown. Asenapine exhibits high affinity for serotonin 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2B, 5-HT2C, 5-...
Status:
US Approved Rx (2016)
First approved in 1997

Class (Stereo):
CHEMICAL (ACHIRAL)



Quetiapine, marketed as SEROQUEL XR, is an atypical antipsychotic approved for the treatment of schizophrenia, bipolar disorder, and along with an antidepressant to treat major depressive disorder. The mechanism of action of SEROQUEL XR in the treatm...
Status:
US Approved Rx (2021)
First approved in 1996

Class (Stereo):
CHEMICAL (ACHIRAL)



Olanzapine is a novel antipsychotic agent marketed by Lilly & Co. It has a pleotrophic pharmacology and affects dopaminergic, serotonergic, muscarinic and adrenergic activities. Olanzapine is used to treat the symptoms of psychotic conditions suc...
Status:
US Approved Rx (2002)
First approved in 1989

Class (Stereo):
CHEMICAL (ACHIRAL)



Clozapine was discovered in 1958 by an anesthetist and now it is used for the treatment of schizophrenia. Although the exact mechanism of its action is unknown, the effect of clozapine on schizophrenia is associated with inhibition of dopamine D2 and...
Status:
US Approved Rx (1988)
First approved in 1975

Class (Stereo):
CHEMICAL (ACHIRAL)



Loxapine is a dibenzoxazepine tricyclic antipsychotic agent, available for oral and inhalatory administration, classified as a typical antipsychotic. Loxapine acts as an antagonist at central serotonin and dopamine receptors. Adasuve (loxapine inhala...
Status:
Possibly Marketed Outside US
First approved in 2020

Class (Stereo):
CHEMICAL (ACHIRAL)



Clothiapine is a neuroleptic of dibenzoepine class that ise used for the treatment of mental disorders. It is supposed that clothiapine acts by blocking GABA (A) receptors. The drug is marketed in some European countries under the name Entumin.