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Showing 1 - 10 of 32 results

Status:
US Approved Rx (2010)
First approved in 2001

Class (Stereo):
CHEMICAL (ABSOLUTE)



Bimatoprost (marketed in the US, Canada and Europe by Allergan, under the trade name Lumigan) ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is...
Status:
US Approved Rx (2022)
First approved in 1996

Class (Stereo):
CHEMICAL (ACHIRAL)



Brimonidine reduces the amount of fluid in the eye, which decreases pressure inside the eye. Brimonidine ophthalmic (for the eyes) is used to treat open-angle glaucoma or ocular hypertension (high pressure inside the eye). Brimonidine is an alpha adr...
Status:
US Approved Rx (2008)
First approved in 1994

Class (Stereo):
CHEMICAL (ABSOLUTE)



Dorzolamide is a sulfonamide and a highly specific carbonic anhydrase II (CA-II) inhibitor, which is the main CA isoenzyme involved in aqueous humor secretion. Dorzolamide is marketed under the trade name Trusopt, indicated in the treatment of elevat...
Status:
US Approved Rx (2000)
First approved in 1988

Class (Stereo):
CHEMICAL (RACEMIC)



Carteolol is a nonselective beta-adrenoceptor blocking agent for ophthalmic use. It has been shown to be effective in lowering intraocular pressure and may be used in patients with chronic open-angle glaucoma and intraocular hypertension. It may be u...
Status:
US Approved Rx (1987)
First approved in 1987

Class (Stereo):
CHEMICAL (ACHIRAL)



Apraclonidine (IOPIDINE) is an α2-adrenergic receptor agonist and a weak α1-adrenergic receptor agonist. It is used for the prevention and treatment of postsurgical intraocular pressure elevation. The following adverse events, occurring in less than ...
Status:
US Approved Rx (1985)
First approved in 1985

Class (Stereo):
CHEMICAL (ABSOLUTE)



Levobunolol is a non-cardioselective beta-adrenoceptor blocking agent, equipotent at both beta1 and beta2 adrenergic receptors. Levobunolol is greater than 60 times more potent than its dextro isomer in its beta-blocking activity, yet equipotent in i...
Status:
US Approved Rx (2009)
First approved in 1985

Class (Stereo):
CHEMICAL (RACEMIC)



Betaxolol or SL 75212, (± )-1-(isopropylamino)-3-(p-(cyclopropylmethoxyethyl-phenoxy)2-propranol, is a potent cardioselective beta1-adrenoceptor antagonist devoid of intrinsic sympathomimetic activity with very weak local anaesthetic properties. Oral...
Status:
US Approved Rx (1987)
First approved in 1974

Class (Stereo):
CHEMICAL (ACHIRAL)



Clonidine is a centrally acting α2 adrenergic agonist and imidazoline receptor agonist used to treat high blood pressure, attention deficit hyperactivity disorder, anxiety disorders, tic disorders, withdrawal (from either alcohol, opioids, or smoking...
Status:
US Approved Rx (1993)
First approved in 1966

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Acetylcholine is the neurotransmitter at neuromuscular junctions, at synapses in the ganglia of the visceral motor system, and at a variety of sites within the central nervous system. Whereas a great deal is known about the function of cholinergic tr...
Status:
US Approved Rx (1993)
First approved in 1959

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Methazolamide is topical carbonic anhydrase inhibitor. Methazolamide is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers. Metha...