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Status:
US Approved Rx (2008)
First approved in 1979

Class (Stereo):
CHEMICAL (ACHIRAL)



Metoclopramide is a dopamine D2 antagonist that is used as an antiemetic. Metoclopramide inhibits gastric smooth muscle relaxation produced by dopamine, therefore increasing cholinergic response of the gastrointestinal smooth muscle. It accelerates i...
Status:
Possibly Marketed Outside US
First approved in 2009

Class (Stereo):
CHEMICAL (ACHIRAL)



Domperidone is a peripherally selective D2 receptor antagonist. It acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine. Domperidone was not approved ...