U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
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Showing 1 - 5 of 5 results

Status:
US Approved Rx (2009)
First approved in 1994

Class (Stereo):
CHEMICAL (ACHIRAL)



Lamotrigine (marketed as Lamictal) is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder. The precise mechanism(s) by which lamotrigine exerts its anticonvulsant action are unknown. In animal models designed to detect antic...
Status:
US Approved Rx (1996)
First approved in 1938

Class (Stereo):
CHEMICAL (ACHIRAL)



Phenytoin is an anti-epileptic drug. Phenytoin has been used with much clinical success against all types of epileptiform seizures, except petit mal epilepsy. Phenytoin is a available for oral administration (tablets, capsules, suspension). CEREBYX®...
Status:
US Approved Rx (2000)
First approved in 2000

Class (Stereo):
CHEMICAL (ACHIRAL)



Oxcarbazepine and its active metabolite (10,11-dihydro-10-hydroxy-carbazepine, MHD) have been effective in animal models of epilepsy that generally predict efficacy in generalized tonic-clonic seizures and partial seizures in humans. The pharmacokin...
Status:
US Approved Rx (2022)
First approved in 1968

Class (Stereo):
CHEMICAL (ACHIRAL)



Carbamazepine is an analgesic, anti-epileptic agent that is FDA approved for the treatment of epilepsy, trigeminal neuralgia. It appears to act by reducing polysynaptic responses and blocking the post-tetanic potentiation. It depresses thalamic poten...
Status:
US Approved Rx (1996)
First approved in 1938

Class (Stereo):
CHEMICAL (ACHIRAL)



Phenytoin is an anti-epileptic drug. Phenytoin has been used with much clinical success against all types of epileptiform seizures, except petit mal epilepsy. Phenytoin is a available for oral administration (tablets, capsules, suspension). CEREBYX®...