U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Showing 1 - 3 of 3 results

Status:
US Approved Rx (2003)
First approved in 1994

Class (Stereo):
CHEMICAL (ABSOLUTE)

Targets:


Vinorelbine (trade name Navelbine) is a semi-synthetic vinca-alkaloid with a broad spectrum of anti-tumour activity. Vinorelbine is a mitotic spindle poison that impairs chromosomal segregation during mitosis. It blocks cells at G2/M. Microtubules (...
Status:
US Approved Rx (1988)
First approved in 1963

Class (Stereo):
CHEMICAL (ABSOLUTE)



Vincristine is a vinca alkaloid antineoplastic agent used as a treatment for various cancers including breast cancer, Hodgkin's disease, Kaposi's sarcoma, and testicular cancer. The vinca alkaloids are structurally similar compounds comprised of 2 mu...
Status:
US Approved Rx (1987)
First approved in 1961

Class (Stereo):
CHEMICAL (ABSOLUTE)

Targets:


Vinblastine is a Vinca alkaloid obtained from the Madagascar periwinkle plant. Vinca alkaloids were found out in the 1950's by Canadian scientists, Robert Noble and Charles Beer for the first time. Medicinal applications of this plant lead to the mon...