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Development Status
Other
327
Investigational
208
US Approved Rx
200
Possibly Marketed Outside US
175
US Previously Marketed
62
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Primary Target
Dopamine D2 receptor
297
Dopamine transporter
180
Norepinephrine transporter
120
Dopamine D1 receptor
101
Dopamine D3 receptor
91
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Highest Phase
Approved
371
Phase II
40
Not Provided
34
Phase III
27
Phase I
13
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Approval Year
Unknown
692
1959
21
1997
16
1961
15
1937
14
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Condition
Schizophrenia
170
Unknown
66
Parkinson's disease
65
Depression
38
Major depressive disorder
36
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Treatment Modality
Primary
512
Palliative
43
Preventing
34
Diagnostic
10
Secondary
10
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CNS Activity
CNS Active
485
CNS Penetrant
67
CNS Non-penetrant
14
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Originator
Eli Lilly
18
Pfizer
17
Smith Kline & French Laboratories
14
Lundbeck
13
Rhône-Poulenc
12
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Substance Class
Chemical
966
Protein
17
Mixture
5
Structurally Diverse
4
Concept
1
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INN Stem
Chemical substance(-ine)
5
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GInAS Tag
KEW
1
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Code System
FDA UNII
993
PUBCHEM
958
CAS
949
EPA CompTox
738
SMS_ID
521
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Protein Type
RECEPTOR
4
ENZYME
1
TRANSPORTER
1
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ATC Level 1
NERVOUS SYSTEM
104
ALIMENTARY TRACT AND METABOLISM
15
CARDIOVASCULAR SYSTEM
11
GENITO URINARY SYSTEM AND SEX HORMONES
10
RESPIRATORY SYSTEM
6
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ATC Level 2
PSYCHOLEPTICS
61
PSYCHOANALEPTICS
19
ANTI-PARKINSON DRUGS
15
CARDIAC THERAPY
9
OTHER GYNECOLOGICALS
9
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ATC Level 3
ANTIPSYCHOTICS
60
DOPAMINERGIC AGENTS
14
ANTIDEPRESSANTS
10
PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
9
CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
8
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ATC Level 4
Centrally acting sympathomimetics
9
Dopamine agonists
9
Other antipsychotics
9
Adrenergic and dopaminergic agents
8
Phenothiazines with piperazine structure
8
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Substance Form
Principal Form
574
Salts, Hydrates, Esters, etc.
419
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Matches
22 fields
Approximate Matches
202
Related Substance Name
195
Code Comments
67
Reference Text / Citation
27
Standardized Name
27
Any Name
25
Relationship Comments
19
Display Name
6
Note
5
Code Literal
4
WIKIPEDIA
3
Reference URL
1
LACTMED
1
Code URL
1
WHO INTERNATIONAL PHARMACOPEIA
1
root_structurallyDiverse_fractionName
Exact Matches
21
Related Substance Name
1
Display Name
1
Standardized Name
1
Code Literal
1
Any Name
1
LACTMED
1
WIKIPEDIA
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