U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

Showing 901 - 910 of 13125 results

Status:
Investigational
Source:
NCT02322086: Phase 2 Interventional Completed Psoriasis
(2015)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Rose Bengal lactone is a polyhalogenated derivative of Fluorescein. Rose Bengal lactone is a dye compound described to produce cell membrane damage. Rose Bengal lactone and other Fluorescein derivatives are also described to modulate the function of ATP-sensitive K+ channels. Rose bengal lactone reacts readily with bases so treatment with triethylamine immediately yields the Rose Bengal salt.
Cycloheximide is an antibiotic produced by fermentation culture of Streptomyces griseus, Streptomyces noursei, Streptomyces albulus, Streptomyces naraensis, or other cycloheximide-producing microorganism. It was first discovered by A. Whiffen et al. in 1946. She observed the activity of the compound against the yeasts and it became known as the first antifungal antibiotic. Cycloheximide has been marketed as a plant fungicide for many years and this use continues mainly against fungal diseases of turf and for powdery mildew on roses. More recently, cycloheximide has been recognized and is being developed as an abscission agent for citrus fruits and olives. Due to significant toxic side effects, including DNA damage, teratogenesis, and other reproductive effects, cycloheximide is generally used only in in vitro research applications, and is not suitable for human use as a therapeutic compound. Cycloheximide is an antimitotic and an inhibitor of the synthesis of both DNA and protein.
Status:
Investigational
Source:
INN:picolamine [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Picolylamine (PA), a derivatizing agent displaying a highly ESI-active pyridyl group that reacts with carboxylic acids in the presence of a condensation agent to form an amide derivative. Picolylamine is used as a derivatization reagent for the detection of endogenous carboxylic acids.
Status:
Investigational
Source:
USAN:DIOTYROSINE I 125 [USAN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Diotyrosine I 125 is the diagnostic aid.
Status:
Investigational
Source:
INN:glidazamide
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Glidazamide is an antidiabetic drug. It is a hypoglycemic agent that is part of the second-generation sulfonamide urea derivatives.
Status:
Investigational
Source:
INN:metoquizine
Source URL:

Class (Stereo):
CHEMICAL (UNKNOWN)

Metoquizine is a muscarinic acetylcholine receptor antagonist that was used as anti-ulcerative. Information about the current use of this compound is not available.
Status:
Investigational
Source:
INN:cortodoxone
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



11-Deoxycortisol (also known as cortodoxone) is the predominant deoxycorticosteroid and is the immediate precursor of cortisol, which is formed by the enzymatic action of 11beta-hydrozylase (P450). Deficiency of this enzyme causes congenital adrenal hyperplasia, which is characterized by hypertension. 11-deoxycortisol is measured as part of the Metyrapone Test. Metyrapone blocks the formation of cortisol, resulting in increased secretion of Adrenocorticotropic hormone (ACTH) and 11-deoxycortisol in normal individuals.
Status:
Investigational
Source:
INN:nifurquinazol
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Nifurquinazol, a 5-nitrofuran derivative, is an antibacterial agent.
Status:
Investigational
Source:
Invest New Drugs. Feb 1990;8(1):113-9.: Phase 2 Human clinical trial Completed Soft Tissue Neoplasms
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)