U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 81 - 90 of 165 results

Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Possibly Marketed Outside US
Source:
Lung Guarder by Hainan Zehuitang Biotechnology Co., LTD
(2024)
Source URL:
First approved in 2024
Source:
Lung Guarder by Hainan Zehuitang Biotechnology Co., LTD
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Targets:

Status:
Possibly Marketed Outside US
Source:
Acetylspiramycin
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



Acetylspiramycin for spiramycin acetylated derivatives, belonging to 16 membered ring macrolide. It is suitable for sensitive Staphylococcus, Streptococcus and Streptococcus pneumoniae induced by mild to moderate infections, such as pharyngitis, tonsillitis, sinusitis, otitis media, periodontitis, acute bronchitis, chronic bronchitis, pneumonia, non-gonococcal urethritis, skin and soft tissue infection, can be used for the selection of drugs for cryptosporidiosis, or as a treatment for pregnancy women of toxoplasmosis. The mechanism for Acetylspiramycin combined with sensitive microbial 50S ribosomal subunit, RNA dependent inhibition of protein synthesis and bacteriostasis.
Status:
Possibly Marketed Outside US
Source:
Pyrethrins/piperonyl butoxide by Egyesult Gyogyszer es Tapszergyar
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



Pyrethrins are natural insecticides derived from chrysanthemum flowers containing a mixture of six components: pyrethrin I, cinerin I, jasmolin I, pyrethrin II, cinerin II, and jasmolin II. Pyrethrins induce a toxic effect in insects when they penetrate the cuticle and reach the nervous system. Pyrethrins bind to sodium channels that occur along the length of nerve cells. Sodium channels are responsible for nerve signal transmission along the length of the nerve cell by permitting the flux of sodium ions. When pyrethrins bind to sodium channels, normal function of the channels is obstructed thereby resulting in hyperexcitation of the nerve cell and, consequently, a loss of function of the nerve cell. The shutdown of the insect nervous system and death are most often the consequences of insect exposure to pyrethrins. Pyrethrin II has strong activity against Plasmodium falciparum.
mixture
Status:
Investigational
Source:
USAN:IPROCINODINE HYDROCHLORIDE [USAN]
Source URL:

Class:
MIXTURE

IPROCINODINE, a semisynthetic antibiotic, is a mixture of the isopropylated cinodine I and cinodide II, glycolipid antibiotics isolated from Nocardia species.