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Class (Stereo):
CHEMICAL (ACHIRAL)
Recainam is an investigational Class I anti-arrhythmic agent that has been studied for its potential in treatment of heart rhythm disorders. No severe adverse events of intravenous recainam adminstration were reported in a study in patients with frequent ventricular premature complexes (extra heart beats) and nonsustained ventricular tachycardia (abnormally fast heartbeat).
Class (Stereo):
CHEMICAL (ACHIRAL)
Brinazarone (SR33557) is a calcium channel blocker, that inhibits acid sphingomyelinase activity and enhances ricin-A chain immunotoxin activity. Brinazarone may act, much like perhexiline, by disturbing membrane lipid composition through their inhibitory action on lysosomal phospholipid hydrolases, such as acid sphingomyelinase, leading to modifications in intracellular routing and to subsequent degradation of ricin-A chain immunotoxins.
Class (Stereo):
CHEMICAL (ACHIRAL)
Bisfentidine (DA-5047), a histamine-2 receptor antagonist was studied for the treatment of colds and gingivitis.
Class (Stereo):
CHEMICAL (ABSOLUTE)
Opaviraline (also known as GW 420867), a nonnucleoside reverse transcriptase inhibitor that was studied for the treatment of HIV infections. The drug participated in clinical trials phase II in Germany, in South Africa, and in the United Kingdom, however, these studies were discontinued.
Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
Mipimazole was developed as a thyroid inhibitor. However, information about the further development of the drug is not available.
Class (Stereo):
CHEMICAL (UNKNOWN)
ISOPROFEN is an anti-inflammatory agent with analgesic and antipyretic properties. Its anti-inflammatory potency is greater than that of phenylbutazone but lower than that of indomethacin. Its antipyretic action can be explained by an effect of this substance on the metabolism of arachidonic acid in the brain.
Class (Stereo):
CHEMICAL (ABSOLUTE)
ITURELIX, a decapeptide, is a gonadotropin-releasing hormone antagonist.
Class (Stereo):
CHEMICAL (ABSOLUTE)
IVARIMOD is a hepatoprotectant.
Class (Stereo):
CHEMICAL (ABSOLUTE)
Glenvastatin (HR780) is a synthetic HMG-CoA reductase (HMGCR) inhibitor. Like other statins, glenvastatin shows very low systemic bioavailability due to an extensive first pass effect at the intestinal and/or hepatic level. This is a positive trait, since the liver is the target organ for statins. Evidence has been found that glenvastatin protects the vascular endothelium from oxidant stress and inhibits the migration and proliferation of smooth muscle cells. In rabbits, long-term treatment with glenvastatin reduces the plasma cholesterol level, and decreases the liver cholesterol contents. There are no results of clinical trials for glenvastatin.
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
Caprindolol, also known as SDZ 21009, is a beta-adrenoceptor blocker with affinity for serotonin (5-HT1A and 5-HT1B receptors.