IVARIMOD

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C30H44N2O5
Molecular Weight	512.6808
Optical Activity	UNSPECIFIED
Defined Stereocenters	8 / 8
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)C1=C[C@@]23CC[C@@H]4[C@](C)(CCC[C@@]4(C)C(=O)N5CCOCC5)[C@H]2C[C@@H]1[C@@H]6[C@H]3C(=O)N(CCO)C6=O

InChI

InChIKey=YBWSFBMTGQZOMO-JKMJZXPOSA-N

InChI=1S/C30H44N2O5/c1-18(2)20-17-30-9-6-21-28(3,7-5-8-29(21,4)27(36)31-11-14-37-15-12-31)22(30)16-19(20)23-24(30)26(35)32(10-13-33)25(23)34/h17-19,21-24,33H,5-16H2,1-4H3/t19-,21+,22+,23+,24-,28-,29+,30-/m0/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1037274 | https://www.ncbi.nlm.nih.gov/pubmed/1037273

IVARIMOD is a hepatoprotectant.

Approval Year

PubMed

Title	Date	PubMed
The protective effect of a novel compound RU 18492, on galactosamine-induced hepatotoxicity in the rat.	1976	1037274
Preliminary studies on the absorption, distribution and excretion of N-(2-hydroxyethyl)-maleopimarimidyl morpholide (3H-RU 18492) in the female rat and dog.	1976	1037273

Name

Type

Language

4-(((3AR,3BS,5AR,6R,9AR,9BR,11R,11AR)-1,2,3,3A,4,5,5A,6,7,8,9,9A,9B,10,11,11A-HEXADECAHYDRO-2-(2-HYDROXYETHYL)-12-ISOPROPYL-6,9A-DIMETHYL-1,3-DIOXO-3B,11-ETHENO-3BH-NAPHTH(2,1-E)ISOINDOL-6-YL)CARBONYL)MORPHOLINE

Preferred Name

English

IVARIMOD

Official Name

English

ivarimod [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C308