U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 871 - 880 of 13268 results

Status:
Investigational
Source:
INN:iofratol
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Iofratol, is a dimeric, hexaiodinated radiographic contrast agent that was being developed by Bracco as a potential X-ray contrast medium for angiography and myelography.
Status:
Investigational
Source:
NCT01000493: Phase 2 Interventional Completed Post-Traumatic Stress Disorder
(2009)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



Orvepitant is a novel generation brain penetrant, selective and potent, small molecule NK-1 receptor antagonist. Orvepitant’s (GW823296) mode of action and developability characteristics made it a suitable development candidate for the treatment of common anxiety disorders, posttraumatic stress disorder and major depressive disorder. It’s in phase II clinical trials as an effective inhibitor of itch-associated response.
Status:
Investigational
Source:
NCT02194465: Phase 2 Interventional Completed Primary Hypertension
(2014)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT00923520: Phase 1 Interventional Completed Renal Cell Carcinoma
(2009)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:salprotoside
Source URL:

Class (Stereo):
CHEMICAL (EPIMERIC)

Status:
Investigational
Source:
NCT01154621: Phase 1 Interventional Completed Tolerability
(2010)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
INN:gemazocine
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Gemazocine is an opioid antagonist. It was first reported in the literature in the 1970’s, and toxicology studies have been performed to characterize its profile.
Status:
Investigational
Source:
INN:tolquinzole [INN]
Source URL:

Class (Stereo):
CHEMICAL (MIXED)

Tolquinzole is an antidepressant agent.
Status:
Investigational
Source:
INN:truxipicurium iodide
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Truxipicurium, a derivative of alpha-truxillic acid, a curare-like drug, is a neuromuscular blocking agent with rigid structure.
Status:
Investigational
Source:
INN:pamatolol
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Pamatolol is a beta-Adrenergic receptor antagonist was studied as an Antiarrhythmic agent. The phase I clinical trial has shown that the drug was relatively cardioselective in man. Information about the further development of this drug is not available.